Results 81 to 90 of about 3,156,718 (320)

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Conceptual and Technical Design Aspects of Accelerators for External Injection in LWFA

open access: yesApplied Sciences, 2018
Laser driven Wake-Field Acceleration (LWFA) has proven its capability of accelerating electron bunches (e-bunches) to up to 4 GeV energy in a single stage while reaching gradients up to hundreds of GV/m.
Barbara Marchetti   +3 more
doaj   +1 more source

Poisson matching

open access: yesAnnales de l'Institut Henri Poincaré, Probabilités et Statistiques, 2009
37 pages; to appear in Annales de l'institut Henri Poincare (B)
Holroyd, Alexander E.   +3 more
openaire   +3 more sources

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

A Necessary and Sufficient Condition for Graph Matching to be equivalent to Clique Search [PDF]

open access: yes, 2009
This paper formulates a necessary and sufficient condition for a generic graph matching problem to be equivalent to the maximum vertex and edge weight clique problem in a derived association graph.
Jain, Brijnesh
core  

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

MatchZoo: A Learning, Practicing, and Developing System for Neural Text Matching

open access: yes, 2019
Text matching is the core problem in many natural language processing (NLP) tasks, such as information retrieval, question answering, and conversation.
Cheng, Xueqi   +3 more
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

A New, Score-Based Multi-Stage Matching Approach for Road Network Conflation in Different Road Patterns

open access: yesISPRS International Journal of Geo-Information, 2019
Road-matching processes establish links between multi-sourced road lines representing the same entities in the real world. Several road-matching methods have been developed in the last three decades.
Müslüm Hacar, Türkay Gökgöz
doaj   +1 more source

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