Results 111 to 120 of about 7,691,602 (298)
Maximum Matching in Multi-Interface Networks
Theoretical Computer Science, 2012 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Adrian Kosowski +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Matching of Energy Provisions in Multihop Wireless Infra-Structures
Energies, 2016 Recently there have been large advances in energy technologies for battery-operated systems, including green energy resources and high capacity batteries.
Rui Teng +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
MAP-MATCHING IN COMPLEX URBAN ROAD NETWORKS [PDF]
Revista Brasileira de Cartografia, 2003 Global Navigation Satellite Systems (GNSS) such as GPS and digital road maps can be used for land vehicle navigation systems. However, GPS requires a level of augmentation with other navigation sensors and systems such as Dead Reckoning (DR) devices, in ...
R. B. Noland, M. Quddus, W. Y. Ochieng
doaj
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Anatomy Ontology Matching Using Markov Logic Networks
Scientifica, 2016 The anatomy of model species is described in ontologies, which are used to standardize the annotations of experimental data, such as gene expression patterns.
Chunhua Li +3 more
doaj +1 more source
Reconciling Schema Matching Networks
, 2014 Keywords: data integration ; schema matching ; reconciliation ; crowdsourcing ; collaborative work ; argumentation These Ecole polytechnique federale de Lausanne EPFL, n° 6033 (2013)Programme doctoral Informatique, Communications et InformationFaculte informatique et communicationsInstitut d'informatique fondamentaleLaboratoire de systemes d ...
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FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source