Results 71 to 80 of about 7,691,602 (298)
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
A hidden Markov model for matching spatial networks
Journal of Spatial Information Science, 2019 Datasets of the same geographic space at different scales and temporalities are increasingly abundant, paving the way for new scientific research. These datasets require data integration, which implies linking homologous entities in a process called data
Benoit Costes, Julien Perret
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Heterogeneous Graph Matching Networks
CoRR, 2019 Information systems have widely been the target of malware attacks. Traditional signature-based malicious program detection algorithms can only detect known malware and are prone to evasion techniques such as binary obfuscation, while behavior-based approaches highly rely on the malware training samples and incur prohibitively high training cost.
Shen Wang 0005 +9 more
openaire +2 more sources
Matching Matched Filtering with Deep Networks for Gravitational-Wave Astronomy [PDF]
Physical Review Letters, 2018 5 pages, 3 figures, submitted to ...
Gabbard, Hunter +3 more
openaire +4 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The Synergistic Effects of Structural Evolution and Attack Strategies on Network Matching Robustness
EntropyResearch on network robustness has long focused on changes in the structure connectivity of networks under attacks, effectively depicting structural integrity while ignoring the exploration of functional integrity.
Xu Na +4 more
doaj +1 more source
An Analysis of the Matching Hypothesis in Networks
PLOS ONE, 2015 The matching hypothesis in social psychology claims that people are more likely to form a committed relationship with someone equally attractive. Previous works on stochastic models of human mate choice process indicate that patterns supporting the matching hypothesis could occur even when similarity is not the primary consideration in seeking partners.
Tao Jia +3 more
openaire +5 more sources
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source