Results 41 to 50 of about 629,769 (266)
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Ramsey Numbers of Connected Clique Matchings
The Electronic Journal of Combinatorics, 2017 We determine the Ramsey number of a connected clique matching. That is, we show that if $G$ is a $2$-edge-coloured complete graph on $(r^2-r-1)n-r+1$ vertices, then there is a monochromatic connected subgraph containing $n$ disjoint copies of $K_r$, and that this number of vertices cannot be reduced.
openaire +4 more sources
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
On the nullity number of graphs
Electronic Journal of Graph Theory and Applications, 2017 The paper discusses bounds on the nullity number of graphs. It is proved in [B. Cheng and B. Liu, On the nullity of graphs. Electron. J. Linear Algebra 16 (2007) 60--67] that $\eta \le n - D$, where $\eta$, n and D denote the nullity number, the order ...
Mustapha Aouchiche, Pierre Hansen
doaj +1 more source
Extremal Values of Variable Sum Exdeg Index for Conjugated Bicyclic Graphs
Journal of Chemistry, 2021 A connected graph GV,E in which the number of edges is one more than its number of vertices is called a bicyclic graph. A perfect matching of a graph is a matching in which every vertex of the graph is incident to exactly one edge of the matching set ...
Muhammad Rizwan +3 more
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Restricted Size Ramsey Number Involving Matching and Graph of Order Five
Journal of Mathematical and Fundamental Sciences, 2020 Harary and Miller (1983) started the research on the (restricted) size Ramsey number for a pair of small graphs. They obtained the values for some pairs of small graphs with order not more than four.
Denny Riama Silaban +2 more
doaj +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
On Bond Incident Degree Indices of Fixed-Size Bicyclic Graphs with Given Matching Number
MathematicsA connected graph with p vertices and q edges satisfying q=p+1 is referred to as a bicyclic graph. This paper is concerned with an optimal study of the BID (bond incident degree) indices of fixed-size bicyclic graphs with a given matching number. Here, a
Akbar Ali +6 more
doaj +1 more source