Results 61 to 70 of about 629,769 (266)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Image reconstruction algorithm based on variable atomic number matching pursuit

open access: yesJournal of Algorithms & Computational Technology, 2017
As the most critical part of compressive sensing theory, reconstruction algorithm has an impact on the quality and speed of image reconstruction. After studying some existing convex optimization algorithms and greedy algorithms, we find that convex ...
Hongtu Zhao, Chong Chen, Chenxu Shi
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

New Results on Graph Matching from Degree-Preserving Growth

open access: yesMathematics
The recently introduced model in S. R. Kharel et al.’s study [Degree-preserving network growth. Nature Physics 2022, 18, 100–106] uses matchings to insert new vertices of prescribed degrees into the current graph of an ever-growing graph sequence.
Péter L. Erdős   +3 more
doaj   +1 more source

The Maximum Number of Dominating Induced Matchings

open access: yesJournal of Graph Theory, 2014
AbstractA matching M of a graph G is a dominating induced matching (DIM) of G if every edge of G is either in M or adjacent with exactly one edge in M. We prove sharp upper bounds on the number of DIMs of a graph G and characterize all extremal graphs.
Lin, Min Chih   +3 more
openaire   +3 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Dominating induced matchings and other graph parameters

open access: yesAKCE International Journal of Graphs and Combinatorics
A matching M in a graph G is an induced matching if the largest degree of the subgraph of G induced by M is equal to one. A dominating induced matching (DIM) of G is an induced matching that dominates every edge of G. It is well known that, if they exist,
A. Mahmoodi   +3 more
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Extremal hypergraphs for matching number and domination number

open access: yesDiscrete Applied Mathematics, 2018
A matching in a hypergraph $\mathcal{H}$ is a set of pairwise disjoint hyperedges. The matching number $ (\mathcal{H})$ of $\mathcal{H}$ is the size of a maximum matching in $\mathcal{H}$. A subset $D$ of vertices of $\mathcal{H}$ is a dominating set of $\mathcal{H}$ if for every $v\in V\setminus D$ there exists $u\in D$ such that $u$ and $v$ lie in ...
Erfang Shan   +3 more
openaire   +3 more sources

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