Results 141 to 150 of about 522,025 (259)

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Will Monkeys Wager Differently as a Function of Stimulus Fluency or When Making Immediate Versus Delayed Judgments of Memory?

open access: yesPsychological Topics
Nonhuman animals can engage in forms of metacognitive control and monitoring processes. However, very little testing of the relation between fluency and metacognition has been done in animals, and little research has assessed memory performance in ...
Michael J. Beran, Kathleen Friedlein
doaj  

Simultaneous and delayed matching-to sample in children

open access: yes, 1966
Matching-to-sample usually involves the presentation of a stimulus, the sample, and several other stimuli, the matches, with the requirement that the subject find a stimulus in the latter array which matches the sample. ln visual matching-to-sample tasks
Sanders, Beverly Jean.
core  

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Performance in delayed non-matching to sample task predicts the diagnosis of obsessive-compulsive disorder. [PDF]

open access: yesTransl Psychiatry, 2019
Maatoug R   +5 more
europepmc   +1 more source

Moral hazard and the demand for health services: A matching estimator approach. [PDF]

open access: yes
We estimate the impact of extra health insurance coverage beyond a National Health System on the demand for several health services. Traditionally, the literature has tried to deal with the endogeneity of the private (extra) insurance decision by finding
Sanz-de-Galdeano, Anna   +2 more
core  

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

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