Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Comparative evaluation over time during mate choice in the green swordtail <i>Xiphophorus hellerii</i>. [PDF]
Bullough K, Kuijper B, Kelley LA.
europepmc +1 more source
Assortative mating and mate-choice contributes to the maintenance of a developmental dimorphism in Streblospio benedicti. [PDF]
Ruskie EL, Zakas C.
europepmc +1 more source
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
UV-Induced Fluorescence in the Balance: Mate Choice and Predation Risk in the Female Ornamented Jumping Spiders. [PDF]
Zhou Y, Yu L, Wang X, Li D, Xu X.
europepmc +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Correction: Zhou et al. (2025). Financial Status of Model, Target, and Observer Modulates Mate Choice Copying and the Mediating Effect of Personality. Behavioral Sciences, 15(10), 1324. [PDF]
Zhou G, Ma S, Wu D.
europepmc +1 more source
Parental Interference in Offspring's Mate Choice: Sets of Actions and Counteractions Based on Both Perspectives. [PDF]
Fišerová A +4 more
europepmc +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source

