Results 111 to 120 of about 361,301 (299)

Predictive Lung- and Spleen-Targeted mRNA Delivery with Biodegradable Ionizable Lipids in Four-Component LNPs

Pharmaceutics
Background/Objectives: Lipid nanoparticles (LNPs) are leading mRNA delivery vehicles, with ionizable lipids (ILs) as their key component. However, the relationship between the IL structure and LNP endogenous organ-targeting is not well understood.
Juan Heredero, Álvaro Peña, Esther Broset, Beatriz Blandín, Diego de Miguel, Teresa Alejo, Alfonso Toro, Elena Mata, Alexandre López-Gavín, Ana Gallego-Lleyda, Diego Casabona, Verónica Lampaya, Ana Larraga, Esther Pérez-Herrán, David Luna, Irene Orera, Eduardo Romanos, Alba García, Juan Martínez-Oliván, Javier Giménez-Warren   +19 more
doaj   +1 more source

Bioinformatics-Based Identification of Human B-Cell Receptor (BCR) Stimulation-Associated Genes and Putative Promoters

BioMedInformatics
Genome engineered B-cells are being developed for chronic, systemic in vivo protein replacement therapies and for localized, tumor cell-actuated anticancer therapeutics.
Ethan Deitcher, Kirk Trisler, Branden S. Moriarity, Caleb J. Bostwick, Fleur A. D. Leenen, Steven R. Deitcher   +5 more
doaj   +1 more source

‘Childish’ and ‘Minors’? Deconstructing Prejudice and Identity Transformation Among Spanish Women Religious During the Long Sixties1

Gender &History, EarlyView.
ABSTRACT This article explores the identity formation process undertaken by Spanish women's religious following the aggiornamento promoted by the Second Vatican Council. Specifically, it seeks to examine the context in which these women lived and acted, analysing the construction of their identities, their capacity for agency and transgression within ...
Verónica García‐Martín
wiley   +1 more source

Mateo Salado

, 2019
Folleto informativo sobre el complejo arqueológico Mateo Salado.
Ministerio de Cultura, Qhapaq Ñan
openaire   +1 more source

ORCHESTRATING DIFFERENCE AND SIMILARITY: Black Fungibility, and the Spatial Redrawing of Racial Categories in Spanish Colonial Morocco, Sahara and Guinea

International Journal of Urban and Regional Research, EarlyView.
Abstract In this article I dissect the spatial strategies through which the Spanish attempted to orchestrate both racial difference and similarity in the African colonies of Morocco, Western Sahara and Equatorial Guinea during the first half of the twentieth century.
Pol Fité Matamoros
wiley   +1 more source

P428: SYK INHIBITION DRIVES DEEP RESPONSES IN A BIOMARKER GUIDED SUBSET OF AML ALONE AND IN RATIONAL COMBINATIONS

HemaSphere, 2022
M. McKeown, L. A. Carvajal, M. A. Day, C. Noe, P. Kumar, J. DiMartino, D. Saffran   +6 more
doaj   +1 more source

Tokenism in Context: Unpacking Token Women Directors in the Corporate Boardroom

Human Resource Management Journal, EarlyView.
ABSTRACT Tokenism in the corporate boardroom is a contemporary human resource management (HRM) issue for academics, practitioners and policy makers. This essay critiques the existing understanding of the concepts of tokens and tokenism in mainstream management and corporate governance scholarship within the particular context of women on corporate ...
Tanusree Jain, Harry J. van Buren III, Deirdre Ahern   +2 more
wiley   +1 more source

Starving or Stuffing? Plasticity in Wild Boar Body Mass Variations During Summer in a Mediterranean Area

Integrative Zoology, EarlyView.
Assessing drivers of population dynamics helps to mitigate human–wildlife conflicts. In Mediterranean areas, summer aridity reduces resources, potentially affecting ungulates' body condition and reproduction. In a mixed forested‐rural area, wild boar female body mass increased throughout summer in rainy‐mild years and decreased in hot‐dry years.
Martina Calosi, Niccolò Fattorini, Andrea Sforzi, Luca Tonini, Francesco Ferretti   +4 more
wiley   +1 more source

Explorando seres vivos en la ciénaga San Rafael de Cortina, Colombia: proyecto para fortalecer el pensamiento científico infantil y la conciencia ambiental

Voces y Silencios: Revista Latinoamericana de Educación
Este artículo presenta una experiencia pedagógica que buscar promover el pensamiento científico y la conciencia ambiental en niños y niñas de preescolar a través de la observación, indagación y exploración de una ciénaga, reconocida como un ecosistema ...
Isabel Cristina Martínez Janne, Libia del Carmen Villarreal Pérez , Sadith Margarita Prieto Arrieta, Erika Cecilia Vega León   +3 more
doaj   +1 more source

Climatic–Anthropogenic Synergy Drives Escalating Minimum Area Requirements and Connectivity‐Protection Mismatch in a Karst‐Endemic Primate

Integrative Zoology, EarlyView.
Climate change and anthropogenic activities drive antagonistic degradation of landscape connectivity for endangered François’ langur (1987–2024), causing 48.8% habitat loss, north‐south fragmentation, and centroid migration (1.2 km/yr). Despite protected areas buffering connectivity, static management fails dynamic priority habitats; we propose ...
Guangmei Yang, Heqin Cao, Tuo Shen, Jipeng Tian, Yixin Diao, Haijun Su   +5 more
wiley   +1 more source