Results 181 to 190 of about 169,768 (264)

Exploring and Targeting the Connection of Iron and Copper Homeostasis to Neurodegenerative Diseases

MedComm, Volume 7, Issue 6, June 2026.
Iron and copper dyshomeostasis, along with their interactions with key intrinsically disordered proteins (e.g., Aβ, tau, α‐synuclein) have a strong implication in the onset and progression of neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), Prion diseases (PrDs), Huntington's disease (HD), Wilson's disease (WD),
Xin Liu, Lin Jia, Kerong Wu, Mo Chen, Jichao Sun, Chuanbin Yang, Chengchao Xu, Jie Sun, Jigang Wang, Lingyun Dai   +9 more
wiley   +1 more source

Retraction Note: Identification of a novel microRNA-mRNA regulatory biomodule in human prostate cancer. [PDF]

Cell Death Dis
Zhang Y, Jiang F, He H, Ye J, Mao X, Guo Q, Wu SL, Zhong W, Wu CL, Lin N.   +9 more
europepmc   +1 more source

Progress in Natural Products Target Discovery Technology

MedComm, Volume 7, Issue 6, June 2026.
Here, we provide a comprehensive overview of current technologies and recent advancements in therapeutic target discovery for natural products. By systematically synthesizing the principles, methodologies, and practical applications of existing experimental and computational strategies, this work provides a more actionable reference framework for ...
Qiyuan Pan, Xiao Yuan, Jinmei Jin, Xin Luan, Cheng Luo, Hongzhuan Chen, Weidong Zhang, Hao Zhang   +7 more
wiley   +1 more source

Dicaffeoylquinic acid alleviates alcoholic liver disease by targeting PLA2G4B and inhibiting the MAPK signaling pathway. [PDF]

Front Pharmacol
Wang L, Wang H, Miao Y, Hasimu H, Ji T, Huang H, Du G, Aisa HA, Xin X.   +8 more
europepmc   +1 more source

Editorial: Discovery of small molecule lead compounds: a driving force to unravel new anti-cancer targets and mechanisms, volume III. [PDF]

Front Oncol
Zhang Y, Fu L, Wang Y.
europepmc   +1 more source

A Universal Hairy Root Transformation Protocol for Evaluating Editing Efficiency in Dicot Plants

Modern Agriculture, Volume 4, Issue 1, June 2026.
A streamlined workflow for the rapid evaluation of CRISPR‐Cas9 editing efficiency using a universal Agrobacterium rhizogenes–mediated hairy root transformation system. The process encompasses seed germination, explant preparation, bacterial infection, hairy root induction, and comprehensive validation of editing events via Sanger sequencing, PCR ...
Hong Yang, Yirang Jiao, Wenjing Sun, Taotao Zhu, Juan Guo, Huawei Zhang   +5 more
wiley   +1 more source

Mejorar la comunicación sobre la equidad en la salud en la investigación observacional (STROBE Equidad): la lista de verificación ampliada y su elaboración. [PDF]

Rev Panam Salud Publica
Dewidar O, Shamseer L, Melendez-Torres GJ, Akl EA, Ramke J, Wang X, Oloyede O, Young T, Nicholls SG, Marshall Z, Kennedy M, Hardy BJ, Rizvi A, Ghogomu E, Rader T, Waddington HS, Shea B, Nguilefem MN, Ellingwood H, Wolfenden L, Tufte J, Horsley T, Pottie K, Cuervo LG, Juando-Prats C, Feng C, Sharp MK, Little J, Owusu-Addo E, Francis D, Kredo T, Mahande MJ, Chamberlain C, Pantoja T, von Elm E, Bhutta ZA, Tugwell P, Wiysonge CS, Funnell S, Jull J, Mbuagbaw L, Welch V.   +41 more
europepmc   +1 more source

The visible and invisible drivers of biocultural loss in the Amazon

People and Nature, Volume 8, Issue 6, Page 1629-1640, June 2026.
Abstract The Amazon is rapidly approaching an ecological tipping point driven by deforestation, forest degradation and global climate change. These are visible issues that receive increasing political and public attention. However, the accelerating biocultural loss in the Amazon, including the extinction of Indigenous languages, the disruption of ...
Torsten Krause, Mairon G. Bastos Lima, Jesica López, Karolin Obert, Juan A. Samper, Ana Maria Vargas   +5 more
wiley   +1 more source

Structural basis for a central permeation pathway in the P2X1 receptor. [PDF]

Cell Discov
Zhang H, Wu P, Gu Z, Xu Y, Hu W, Yuan Q, Xia B, Xu HE, Gao Z.   +8 more
europepmc   +1 more source

La materia urbana come materia scolastica

, 2022
Cancellieri, Adriano, Cannella, Fabrizia, De Cunto, Giulia   +2 more
openaire   +2 more sources