Glucose Transporter 1 in Health and Disease
As the quintessential facilitator of basal glucose uptake, glucose transporter 1 (GLUT1) is indispensable for maintaining systemic energy homeostasis. This graphical abstract delineates the multidimensional landscape of GLUT1 in normal physiology. It highlights its tissue‐specific metabolic roles—from fueling erythrocytes and fetal development to ...
Yi Tai +3 more
wiley +1 more source
Mejorar la comunicación sobre la equidad en la salud en la investigación observacional (STROBE Equidad): la lista de verificación ampliada y su elaboración. [PDF]
Dewidar O +41 more
europepmc +1 more source
Macrophage: Biological Functions, Diseases, and Therapeutic Targets
Macrophages are sentinel innate immune cells that arise from embryonic precursors and bone marrow monocytes, displaying a functional continuum that transcends the classical M1 (pro‐inflammatory)/M2 (anti‐inflammatory) dichotomy. Under homeostatic conditions, balanced M1/M2 polarization preserves tissue integrity by coordinating immune surveillance ...
Bihang Sun +4 more
wiley +1 more source
Dicaffeoylquinic acid alleviates alcoholic liver disease by targeting PLA2G4B and inhibiting the MAPK signaling pathway. [PDF]
Wang L +8 more
europepmc +1 more source
Editorial: Discovery of small molecule lead compounds: a driving force to unravel new anti-cancer targets and mechanisms, volume III. [PDF]
Zhang Y, Fu L, Wang Y.
europepmc +1 more source
Edge‐selective covalent grafting of poly‐arginine‐11 onto B60 graphene nanoparticles preserves the aromatic basal plane for π‐π immobilization of compound 8, highlighting this promising NEK6 inhibitor as the key therapeutic cargo in a peptide‐graphene nanoplatform for potential delivery.
Beatrice Scagnoli +10 more
wiley +1 more source
Structural basis for a central permeation pathway in the P2X1 receptor. [PDF]
Zhang H +8 more
europepmc +1 more source
Collaboration in Cross‐Jurisdictional Water Quality Governance: A Novel Framework and Case Study
ABSTRACT Collaborative governance is often employed to address the inherent complexity of surface water quality governance and provides a structure for cooperation across federal, tribal, state, and local boundaries. However, although guidance exists for assessing specific dimensions of collaborative governance, tools to comprehensively evaluate the ...
Kinsey Ayers, Julie Padowski
wiley +1 more source
Correction: GluN2A-NMDA receptor inhibition disinhibits the prefrontal cortex, reduces forced swim immobility, and impairs sensorimotor gating. [PDF]
Dong YP +15 more
europepmc +1 more source
ABSTRACT Wildlife trafficking poses a critical threat to global biodiversity, contributes to organized crime, and has disproportionate impacts on underserved and Indigenous communities. Although international legal instruments, such as the Convention on International Trade in Endangered Species of Wild Fauna and Flora, and institutional collaborations,
Chad Patrick Osorio
wiley +1 more source

