This outlines the progress for developing a sleep‐modulating herbal formula (SMF). It begins with the identification of effective compounds and quality control, then uses network pharmacology and molecular docking to explain the mechanisms behind the observation found on the behavioural and neurobiological results in animal study.
Jasmine U. Ting +7 more
wiley +1 more source
Development of a Human IgG1 Monoclonal Antibody Targeting Transferrin Receptor 1 for Antitumor Drug Delivery. [PDF]
Ji T, Zong Z, Gong N, Yan M, Chen S.
europepmc +1 more source
A Global Analysis of Domestic Military Policies Governing Responses to Public Health Emergencies
ABSTRACT Throughout the COVID‐19 pandemic, militaries mobilized at an unprecedented scale to support domestic response efforts. This was consistent with the growing trend of asset mobilization for military operations other than war during public health emergencies.
Kuang Yu Hu +4 more
wiley +1 more source
A senescent tumor cell-derived nanovesicle directly primes splenic T cells to potentiate cancer radiotherapy. [PDF]
Pan J +14 more
europepmc +1 more source
Abstract This study evaluated the performance of various global storm‐resolving models (GSRMs) in simulating the Indian Summer Monsoon (ISM), highlighting the limitations of current global kilometer‐scale models in accurately representing precipitation patterns over the Indian subcontinent.
S. Lekshmi +5 more
wiley +1 more source
Correction: GluN2A-NMDA receptor inhibition disinhibits the prefrontal cortex, reduces forced swim immobility, and impairs sensorimotor gating. [PDF]
Dong YP +15 more
europepmc +1 more source
Abstract The Congo River represents one of the largest freshwater discharges in the Atlantic Ocean. In this study, we investigate the role of mesoscale and submesoscale dynamics in modulating salinity transport, using a 3 km‐resolution realistic numerical simulation.
C. Cardot +10 more
wiley +1 more source
Functional Characterization of the Histidine Kinase BaeS Reveals Critical Residues for BaeSR-Dependent Stress Signaling in <i>Escherichia coli</i>. [PDF]
Chen S +10 more
europepmc +1 more source
Medicine for the Material World
ABSTRACT It is clear that many of the inorganic materials of antiquity have been used both as medicines for human ills and also as agents in technological processes. This paper speculates that there might have been a stronger link between these two functions in the past, based on the concept of “active agents”—materials that are efficacious at curing ...
A. M. Pollard
wiley +1 more source
Potent and selective LSD1 inhibitor DC551040 reveals a promising combination therapy for AML with insight into epigenetic dysregulation. [PDF]
Wang J +24 more
europepmc +1 more source

