Results 181 to 190 of about 3,960,500 (346)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

The flamboyance of things: Handmade material culture in new-wave carnival in New Orleans. [PDF]

J Mater Cult
Kelly BA, Radice M.
europepmc   +1 more source

'It's All Done With Mirrors': V.S. Ramachandran and the Material Culture of Phantom Limb Research. [PDF]

Med Hist, 2016
Guenther K.
europepmc   +1 more source

Material culture in Sixteenth Century Venice: a sample from probate inventories, 1510–1615 [PDF]

This paper presents a panel of data about material culture in early modern Venice. The data are taken from three samples of Venetian probate inventories drawn up voluntarily from Venetian widows in the years 1510–1615, at intervals of roughly fifty years.
Isabella Cecchini
core  

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Dividing time-An absolute chronological study of material culture from Early Iron Age urnfields in Denmark. [PDF]

PLoS One
Rose HA, Meadows J.
europepmc   +1 more source

Criterion-level system for assessing the use of the material and resource potential of a physical culture and sports organization of state ownership

M. V. Shvaykovskaya
openalex   +2 more sources

Osteoclast Formation within a Human Co-Culture System on Bone Material as an In Vitro Model for Bone Remodeling Processes [PDF]

, 2018
Franziska F.-F. Schmid, Claudia Kleinhans, Freia Schmid, Petra J. Kluger   +3 more
openalex   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Making the most of scarce biological resources in the desert: Loptuq material culture in Eastern Turkestan around 1900. [PDF]

J Ethnobiol Ethnomed
Hällzon P, Ötkür Z, Ståhlberg S, Svanberg I.   +3 more
europepmc   +1 more source