Results 131 to 140 of about 9,042,160 (311)

Biennalization? What biennalization?: the documentation of biennials and other recurrent exhibitions [PDF]

open access: yes, 2012
Biennials have been central to the development of contemporary art for decades, but there is a paucity of published material specifically related to this subject.
Grandal Montero, Gustavo
core  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Current Research: Toward a Collaborative Development of a Truly Comprehensive Multi-State Material Culture Database [PDF]

open access: yes, 2018
Throughout the past several years, I have been compiling, with the help of several Caddo researchers, a comprehensive multi-state database primarily composed of whole Caddo vessels from published excavations, private collections, and archaeological ...
McKinnon, Duncan P.
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Developing bilingual expressions pocketbook for secondary students at Assalafiyah Language Center (ALC)

open access: yesJournal of Research on English and Language Learning
The objective of this research was to develop bilingual expressions pocketbook. This research used the type of research and development (RnD) that applied the ADDIE model, which employed five steps, including analysis, design, development ...
Ulul Azmi, Aminah Aminah, Adhan Kholis
doaj   +1 more source

GLOBALISATION, CONCENTRATION OF GENETIC MATERIAL AND THEIR IMPLICATIONS FOR SUSTAINABLE DEVELOPMENT [PDF]

open access: yes
This paper examines impacts, both positive and negative, of globalisation on the selection of a limited gene pool in livestock and agricultural production. This concentration has increased yields at high rates.
Clem Tisdell, Clevo Wilson
core  

Developing Mathematics-Students Worksheet Based On Realistic Approach For Junior High School In Bilingual Program [PDF]

open access: yes, 2011
The aim of this study is to develop mathematics-student worksheet based on realistic approach for junior high school in bilingual program. The criteria used to generate product are valid and practical.
Ariyadi, Wijaya   +2 more
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

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