Results 141 to 150 of about 3,285,334 (317)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Lugari District Development Plan 2008-2012

open access: yes, 2002
The 8th District Development Plan (DDP) for the period 2008-2012 was prepared by the District Planning and Monitoring Unit in close collaboration with members of the various Sector Working Groups (SWGs).

core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Nakuru North District Development Plan 2008-2012

open access: yes, 2009
The 8th District Development Plan (DDP) for the period 2008-2012 was prepared by the District Planning and Monitoring Unit in close collaboration with members of the various Sector Working Groups (SWGs).

core  

Structure Design by Knitting: Combined Wicking and Drying Behaviour in Single Jersey Fabrics Made from Polyester Yarns

open access: yesFibers
The kinetics of liquid transport in textiles are determined by the thermodynamic boundary conditions and the substrate’s structure. The knitting process offers a wide range of possibilities for modifying the fabric structure, making it ideal for high ...
Leon Pauly   +4 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

The land capability classification of Sabah [cartographic material].

open access: yes, 1976
Land classification map series of Sabah showing international, state and residency boundaries, transportation, land use and populated places.; "This map accompanies the Land Resources Study No.25 'The Land Capability Classification of Sabah' published by
Great Britain. Ministry of Overseas Development.
core  

AI in EFL education: teachers’ competence and the roadblocks to teaching material development

open access: yesCogent Education
The role of Artificial Intelligence (AI) in education, particularly in EFL teaching, is gaining prominence. However, despite AI’s growing presence in education, research on Indonesian secondary school EFL teachers’ AI competence in developing learning ...
Agnia Ilma, Zuliati Rohmah
doaj   +1 more source

Development of Boron-Based Materials

open access: yesMaterials
The field of boron-based materials has undergone a significant transformation in recent decades, propelled by the unique chemistry of boron and its ability to form complex, multidimensional structures with exceptional physical, chemical, and electronic properties [...]
openaire   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy