Results 81 to 90 of about 3,285,334 (317)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Shaking Table Tests and Numerical Analysis of a Steel Frame Employing Novel Variable-Coefficient Viscous Dampers

Buildings
Variable-coefficient viscous dampers (VVDs) have a variable annular gap, allowing them to dynamically adjust the damping coefficient at different displacement stages and provide higher damping forces during large displacement phases. This study evaluates
Muhan Liu, Chuying Cao, Zhenyu Zhu, Weizhi Xu, Dongsheng Du, Shuguang Wang, Chuanzhi Sun   +6 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Interoperability in Digital Health: Reference Material [PDF]

, 2019
The growth of digital health strategies has increased health professionals access to their patients health information, but one of the key problems in health informatics remains the lack of interoperability between different information systems.
Inter-American Development Bank
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Developments in the structural science of materials [PDF]

IUCrJ, 2017
Recent developments in the structural science of materials and the growing power of computational methods in this field are discussed.
openaire   +5 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

ABOUT THE INTEGRATION OF B-LEARNING IN EPP TO REINFORCE LEARNER AUTONOMY ABOUT THE INTEGRATION OF B-LEARNING IN EPP TO REINFORCE LEARNER AUTONOMY

Revista de Lingüística y Lenguas Aplicadas, 2009
This article builds on one particular initiative that has been developed for over a year and brings blearningto the English for Professional Purposes classroom within a learner-centred context.
Irina Argüelles Álvarez
doaj  

Pengembangan Bahan Ajar PAI Berbasis Sistem

Nuris Journal of Education and Islamic Studies
This article examines the development of Islamic Education (PAI) learning materials through a systemic approach that views education as an interconnected and interdependent process. Education is conceptualized as a system composed of curriculum, learning
Radinal Mukhtar Harahap, Ahmad Zaki Azzahiri, Rasyidin Rasyidin   +2 more
doaj   +1 more source

Recognition of Spatial Patterns in Stability Structural Material of Iran States in Relation to Human Development Indexes [PDF]

نشریه جغرافیا و برنامه‌ریزی, 2012
Vulnerability of cities for earthquakes argue is a topic that is urban planning experts. This subject has variety of aspects such as stability and by instability of structural material.
Asghar Zarrabi, Raheleh Saniei
doaj