Results 111 to 120 of about 9,803,493 (256)
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Engineering ReportsThe investigation of material flow in friction stir welding (FSW) is regarded as essential for enhancing the understanding of the processes that influence the quality and structural integrity of welded joints.
Mostafa Akbari +2 more
doaj +1 more source
To the question of flowing processes interaction in the logistics of transport-freight complexes of enterprises [PDF]
Transport Problems, 2009 In the article the questions of identification of structure and parameters of material flow and associate with it documentary and informative flows are considered and the principles of their co-operation, representing a basis for optimization of process ...
Ekaterina SIZOVA, Vladimir PARUNAKJAN
doaj
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Two-phase flow experimental studies in micro-models [PDF]
, 2013 The aim of this research project was to put more physics into theories of two-phase flow. The significance of including interfacial area as a separate variable in two-phase flow and transport models was investigated.
Physically-based theory of two-phase flow in porous media including fluid-fluid interfacial area +2 more
core
NIR-MFCO dataset: Near-infrared-based false-color images of post-consumer plastics at different material flow compositions and material flow presentations. [PDF]
Data Brief, 2023 Kroell N +8 more
europepmc +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Supply Chain Factors Contributing to Improved Material Flow Indicators but Increased Carbon Footprint. [PDF]
Environ Sci Technol, 2023 Hata S, Nansai K, Nakajima K.
europepmc +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source