Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
GRAPHIC METHOD FOR MODELING MATERIAL FLOWS IN SUPPLY CHAINS
Хабаршысы. Экономика сериясы, 2018 Estimation and optimization of material flows is one of the pivotal tasks in supply chain manage-ment. In order to solve it, various analytical and simulation models are utilized, and for each specific type of model, both advantages and disadvantages are
Tolujew J.
doaj
Material flow analysis-based assessment of polypropylene-fiber-containing microplastics released from disposable masks: Characterizing distribution in the environmental media. [PDF]
Sci Total Environ, 2023 Hong J, Park HN, Lee S, Song MK, Kim Y.
europepmc +1 more source
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Effect of Temperature and Material Flow Gradients on Mechanical Performances of Friction Stir Welded AA6082-T6 Joints. [PDF]
Materials (Basel), 2022 Ma X +7 more
europepmc +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Prospective Dynamic and Probabilistic Material Flow Analysis of Graphene-Based Materials in Europe from 2004 to 2030. [PDF]
Environ Sci Technol, 2022 Hong H, Part F, Nowack B.
europepmc +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
A Numerical Study on the Effect of Tool Speeds on Temperatures and Material Flow Behaviour in Refill Friction Stir Spot Welding of Thin AA7075-T6 Sheets. [PDF]
Materials (Basel), 2023 Janga VSR, Awang M, Pedapati SR.
europepmc +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source