Results 91 to 100 of about 373,182 (301)

Monte carlo study of the physics performance of a digital hadronic calorimeter

, 2009
A digital hadronic calorimeter using MICROMEGAS as active elements is a very promising choice for particle physics experiments at future lepton colliders.
Adloff, Catherine, Blaha, Jan, Blaising, Jean-Jaques, Chefdeville, Maximilien, Espargiliere, Ambroise, Karyotakis, Yannis   +5 more
core   +3 more sources

Non linear effects in piezoelectric materials

Boletín de la Sociedad Española de Cerámica y Vidrio, 2002
The static and dynamic non-linear behaviours of a soft and a hard zirconate titanate composition are investigated in this paper as a function of electrical and mechanical fields. The calculated Rayleigh coefficients show that they are similar for the permittivity ε ^T₃₃ and the piezoelectric constant and nul
Gonnard, P., Petit, L.
openaire   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Large displacement static analysis of a cantilever Timoshenko beam composed of functionally graded material

Science and Engineering of Composite Materials, 2011
In this study, non-linear static analysis of a cantilever Timoshenko beam composed of functionally graded material (FGM) under a non-follower transversal uniformly distributed load is studied with large displacements and large rotations.
Kocatürk Turgut, Şimşek Mesut, Akbaş Şeref Doğuşcan   +2 more
doaj   +1 more source

Lattice Boltzmann Solution of Concave Longitudinal Fins under Step-changing base Boundary Conditions Associated with Accumulated Nonlinearity [PDF]

Journal of Applied and Computational Mechanics
This article reports the transient numerical solution of concave profile longitudinal fins under two cases of step-changing base boundary conditions involving heat flux and temperature, respectively.
Abhishek Sahu, Shubhankar Bhowmick
doaj   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Investigating reciprocity failure in 1.7-micron cut-off HgCdTe detectors

, 2010
Flux dependent non-linearity (reciprocity failure) in HgCdTe NIR detectors with 1.7 micron cut-off was investigated. A dedicated test station was designed and built to measure reciprocity failure over the full dynamic range of near infrared detectors ...
Biesiadzinski, Tomasz, Lorenzon, Wolfgang, Newman, Robert, Schubnell, Michael, Tarle, Greg   +4 more
core   +1 more source