Results 101 to 110 of about 373,182 (301)

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Friction material (metal reinforcement) analysis of brake pad for light rail train system [PDF]

open access: yes, 2016
Brake friction material is very important in braking system where they convert kinetic energy of moving vehicles to thermal energy by friction during braking process. The purpose of this research is to determine the optimal friction materials composition
Abdul Rahman, Abdul Rashid
core  

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

Version 2.0 – “DYNAblast – A software to obtain the behavior of composite laminated plates subjected to blast loads”

open access: yesSoftwareX
New structural technologies are constantly being developed, especially in the case of high-impact loads, which cause significant demands on the structure's resistance to collapse.
Ana Waldila de Queiroz Ramiro Reis   +2 more
doaj   +1 more source

Non-linear dynamic response and vibration of an imperfect three-phase laminated nanocomposite cylindrical panel resting on elastic foundations in thermal environments

open access: yesScience and Engineering of Composite Materials, 2017
This paper presents an analytical approach to investigate the non-linear dynamic response and vibration of an imperfect three-phase laminated nanocomposite cylindrical panel resting on elastic foundations in thermal environments.
Thu Pham Van, Duc Nguyen Dinh
doaj   +1 more source

Implementation of path following techniques into the finite element code LAGAMINE. Part II: Material non linearity

open access: yes, 2009
This short report concerns the second part of the work performed in ArGEnCo in order to implement advanced incremental-iterative solution techniques into the finite element code LAGAMINE for geometrical and phys- ical non-linear problems.
Charlier, Robert   +2 more
core   +1 more source

Understanding the saturation power of Josephson Parametric Amplifiers made from SQUIDs arrays

open access: yes, 2019
We report on the implementation and detailed modelling of a Josephson Parametric Amplifier (JPA) made from an array of eighty Superconducting QUantum Interference Devices (SQUIDs), forming a non-linear quarter-wave resonator.
Buisson, Olivier   +9 more
core   +3 more sources

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Finite element modelling of cold formed stainless steel columns [PDF]

open access: yes, 2004
This paper describes the results obtained from a finite element investigation into the load capacity of column members of lipped channel cross-section, cold formed from Type 304 stainless steel, subjected to concentric and eccentric compression loading ...
Macdonald, M., Rhodes, J.
core   +3 more sources

Cyclic loading of a heterogeneous non-linear poroelastic material

open access: yesSoft Matter
The solid strain and fluid flux response to cyclic loading of a poroelastic material with material heterogeneity are studied. The effect is found to vary with the type of load and heterogeneity, and is non-negligeable.
Godard, ZC, Moulton, DE, Waters, SL
openaire   +3 more sources

Home - About - Disclaimer - Privacy