Results 41 to 50 of about 1,658,555 (265)

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Material property alterations for phenotypes of heart failure with preserved ejection fraction: A numerical study of subject-specific porcine models

Frontiers in Bioengineering and Biotechnology, 2022
A substantial proportion of heart failure patients have a preserved left ventricular (LV) ejection fraction (HFpEF). This condition carries a high burden of morbidity and mortality and has limited therapeutic options.
Jonathan Weissmann, Christopher J. Charles, Christopher J. Charles, Christopher J. Charles, A. Mark Richards, A. Mark Richards, Choon Hwai Yap, Gil Marom   +7 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Microwear textures associated with experimental near-natural diets suggest that seeds and hard insect body parts cause high enamel surface complexity in small mammals

Frontiers in Ecology and Evolution, 2022
In mammals, complex dental microwear textures (DMT) representing differently sized and shaped enamel lesions overlaying each other have traditionally been associated with the seeds and kernels in frugivorous diets, as well as with sclerotized insect ...
Daniela E. Winkler, Daniela E. Winkler, Daniela E. Winkler, Marcus Clauss, Mugino O. Kubo, Ellen Schulz-Kornas, Ellen Schulz-Kornas, Thomas M. Kaiser, Anja Tschudin, Annelies De Cuyper, Tai Kubo, Tai Kubo, Thomas Tütken   +12 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Comparison of material properties of heel pad between adults with and without type 2 diabetes history: An in-vivo investigation during gait

Frontiers in Endocrinology, 2022
ObjectiveThis study was aimed to compare the material properties of heel pad between diabetes patients and healthy adults, and investigate the impact of compressive loading history and length of diabetes course on the material properties of heel pad ...
Xiong-gang Yang, Zhao-lin Teng, Zhen-ming Zhang, Kan Wang, Ran Huang, Wen-ming Chen, Chen Wang, Li Chen, Chao Zhang, Jia-zhang Huang, Xu Wang, Xin Ma, Xiang Geng   +12 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Fabrication of ZnO@Ag₃PO₄ Core-Shell Nanocomposite Arrays as Photoanodes and Their Photoelectric Properties

Nanomaterials, 2019
In this study, we combine the methods of magnetron sputtering, hydrothermal growth, and stepwise deposition to prepare novel ZnO@Ag3PO4 core-shell nanocomposite arrays structure.
Zao Yi, Xin Li, Hui Wu, Xifang Chen, Hua Yang, Yongjian Tang, Yougen Yi, Junqiao Wang, Pinghui Wu   +8 more
doaj   +1 more source

Material properties of titanium diboride

Journal of Research of the National Institute of Standards and Technology, 2000
The physical, mechanical, and thermal properties of polycrystalline TiB2 are examined with an emphasis on the significant dependence of the properties on the density and grain size of the material specimens. Using trend analysis, property relations, and interpolation methods, a coherent set of trend values for the properties of polycrystalline TiB2 is ...
openaire   +2 more sources

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source