Results 81 to 90 of about 2,099,213 (339)
Designing an Optimal Control Model of a Capacity, Multi-stage Continuous MRP System Considering Delay in Production Lead Time and the Possibility of Reworking and Recycling [PDF]
Journal of Systems Thinking in PracticeIn this paper, we propose a multi-stage continuous-MRP system using an optimal control model, considering the production lead time. In the proposed model, the lead time is specified for ordering work in process during the second stage and for final ...
Mahdi Miri +2 more
doaj +1 more source
Perencanaan Kebutuhan Dan Persediaan Bahan Baku Isolating Cock Untuk Memenuhi Permintaan Pelanggan (PT. PINDAD Persero) [PDF]
, 2017 Isolating cock adalah salah satu komponen dari sistem rem udara kereta api yang diproduksi oleh PT. PINDAD (Persero). Strategi respon terhadap permintaan yaitu make to order, sehingga perusahaan akan memproduksi produk isolating cock jika ada pesanan.
ASEP SYAMSUDDIN ABDUL CHOLIQ, 133010110 +2 more
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Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Cross-collaborative supply chains: serious gaming via a case study [PDF]
, 2013 Collaboration currently is crucial for stakeholders operating in the supply chain. Nevertheless effective and sustainable forms of inter- and intra-supply-chain collaboration are scarce in practice.
Dalmolen, Simon, Katsma, Christiaan
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Selçuk Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2004 Malzeme İhtiyaç Planlama MİP sistemi, stok maliyetlerini azaltırken verimliliği ve müşteri memnuniyetini artırmayıhedefleyen bir üretim yönetim sistemidir.
Turan Paksoy, Fulya Altıparmak
doaj
Research and Implementation of Axial 3D Printing Method for PLA Pipes
Applied Sciences, 2020 Additive manufacturing has been applied in many fields, but its layer-by-layer fabrication process leads to a weak inter-layer bond strength of printed parts, so it cannot meet the higher requirements for mechanical properties of the industry. At present,
Haiguang Zhang +5 more
doaj +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Applied Sciences, 2019 The definition of lot sizes represents one of the most important decisions in production planning. Lot-sizing turns into an increasingly complex set of decisions that requires efficient solution approaches, in response to the time-consuming exact methods
Alfonso R. Romero-Conrado +3 more
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source