Results 111 to 120 of about 18,983,868 (378)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Editorial for the Special Issue: Emerging Energy and Materials Sciences in Halide Perovskites [PDF]

, 2023
Feng Yan, Yuanyuan Zhou, Maria Antonietta Loi, Michael Saliba   +3 more
openalex   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

STS-9: Orbital Workshop Spacelab to Fly on Ninth Shuttle Mission [PDF]

The first non-astronants are discussed. Spacelab is described. Spacelab objectives, Spacelab 1 investigations, atmospheric physics and Earth observations, space plasma physics, solar physics and astronomy, material sciences and technology development ...

core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Protocol for preparation of highly durable superhydrophobic bulks with hierarchical porous structures

STAR Protocols
Summary: Superhydrophobic surfaces face challenges in comprehensive durability when used in extreme outdoor environments. Here, we present a protocol for preparing nanocomposite bulks with hierarchical structures using the template technique. We describe
Yunyun Meng, Binrui Wu, Chaoyi Peng, Suli Xing, Changping Yin, Nan Wu, Manish K. Tiwari, Xian Yi   +7 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Protocol for modeling and simulating lithiation-induced stress in largely deformed spherical nanoparticles using COMSOL

STAR Protocols
Summary: Here, we present a finite element method-based scheme for solving coupled partial differential equations (PDEs) for the analysis of lithiation-induced stress in largely deformed spherical nanoparticles via the PDE module in COMSOL.
Yong Li, Yunpeng Guo, Yunhao Wu, Yin Rao, Kai Zhang, Dashun Liu, Fuqian Yang   +6 more
doaj   +1 more source

Historical Epistemology Meets the Human Sciences [PDF]

, 2011
The paper addresses recent developments in historical epistemology, traces the main inspirational sources that feed this approach, and suggests a possible agenda for closer approximation between historical epistemology and the human sciences in studying ...
Balon, Jan, Dvořák, Tomáš
core  

Hyperpolarized Nanodiamond with Long Spin Relaxation Times

, 2015
The use of hyperpolarized agents in magnetic resonance (MR), such as 13C-labeled compounds, enables powerful new imaging and detection modalities that stem from a 10,000-fold boost in signal.
Boele, Thomas, Gaebel, Torsten, Reilly, David J., Rej, Ewa, Waddington, David E. J.   +4 more
core   +1 more source