Results 111 to 120 of about 17,594,294 (300)

Materials science and ontologies

open access: yes
This chapter starts by discussing the challenges in material innovation for manufacturing and the need for multidisciplinary approaches involving actors from many different communities. Interoperability is a key to address these challenges. The new paradigm of materials digitalisation is introduced, and how this can be supported by ontologies ...
Jesper Friis   +4 more
openaire   +3 more sources

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Health Sciences Planning Council, Planning Assumptions, 1979

open access: yes, 1979
Material is part of University Archives collection #00029.University of Minnesota. Health Sciences Planning Office. (1979). Health Sciences Planning Council, Planning Assumptions, 1979.
University of Minnesota. Health Sciences Planning Office
core  

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Health Sciences Parking Facility, 1973-1975

open access: yes, 1973
Material is part of University Archives collection #00029.University of Minnesota. Health Sciences Planning Office. (1973). Health Sciences Parking Facility, 1973-1975.
University of Minnesota. Health Sciences Planning Office
core  

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Health Sciences Planning Committee, 1974-1975 (1)

open access: yes, 1974
Material is part of University Archives collection #00029.University of Minnesota. Health Sciences Planning Office. (1974). Health Sciences Planning Committee, 1974-1975 (1). Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/
University of Minnesota. Health Sciences Planning Office
core  

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

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