Results 81 to 90 of about 18,983,868 (378)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Mind and material engagement

open access: yesPhenomenology and the Cognitive Sciences, 2018
Material Engagement Theory (MET), which forms the focus of this special issue, is a relatively new development within cognitive archaeology and anthropology, but one that has important implications for many adjacent fields of research in phenomenology ...
L. Malafouris
semanticscholar   +1 more source

Carstairs Scores for Scottish Postcode Sectors, Datazones and Output Areas from the 2011 Census [PDF]

open access: yes, 2014
Carstairs deprivation scores, originally created in 1981, provide a measure of material deprivation. Four census variables (male unemployment, no car ownership, overcrowding and low social class) were used in the creation of the score.
Allik, Mirjam   +3 more
core   +1 more source

Heterogeneous continuous time random walks

open access: yes, 2017
We introduce a heterogeneous continuous time random walk (HCTRW) model as a versatile analytical formalism for studying and modeling diffusion processes in heterogeneous structures, such as porous or disordered media, multiscale or crowded environments ...
Grebenkov, Denis S., Tupikina, Liubov
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Protocol for the preparation of flexible material from the mycelium of wood-decay fungal strains and mechanical property investigation

open access: yesSTAR Protocols
Summary: Extraction of chitin-glucan-based materials from fungi has several advantages over animal-based chitin. Here, we present a protocol for extracting chitin-glucan material from the mycelium of wood-decay fungal strains and investigating its ...
Dhanalakshmi Vadivel, Daniele Dondi
doaj   +1 more source

Livelisystems: a conceptual framework integrating social, ecosystem, development and evolutionary theory [PDF]

open access: yes, 2014
Human activity poses multiple environmental challenges for ecosystems that have intrinsic value and also support that activity. Our ability to address these challenges is constrained, inter alia, by weaknesses in cross disciplinary understandings of ...
Dorward, Andrew
core   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Protocol for low-cost quantification of microplastics through electrochemical impedance spectroscopy from aqueous matrices

open access: yesSTAR Protocols
Summary: We present a protocol to quantify microplastics (MPs) in aqueous matrices by analyzing the solution resistance (Rs) imparted by MPs using electrochemical impedance spectroscopy (EIS).
Almeenu Rasheed, Sovik Das
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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