Results 121 to 130 of about 49,978 (267)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Materiales magnéticos: materiales magnéticos para sensores

open access: yes
El crecimiento y la caracterización de láminas delgadas de NiFe son los objetivos fundamentales de este Trabajo Fin de Grado, además de entender varios fenómenos magnéticos desde los puntos de vista de la Física Cuántica y la Física Experimental. Se exploraron los diferentes tipos de sensores magnéticos más comunes y su funcionamiento básico, ya que el
openaire   +1 more source

Correction to : Synthesis, and evaluation of photophysical properties of a potential DPP-derived photosensitizer for photodynamic therapy with D-A-D architecture. [PDF]

open access: yesJ Mater Sci Mater Med
Escalona Hernández V   +4 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Geopoéticas materiales:

open access: yesAisthesis, 2017
Los poemarios Calamina y Amarillo crepúsculo exhiben espacios y paisajes que adquieren materialidad en el lenguaje poético. A pesar de ser poemarios muy disimiles, en ambos el espacio se configura desde una materialidad atravesada por la modernidad y su despojo. La relación entre paisaje y poesía se aborda desde el concepto de geopoética, trabajado por
openaire   +1 more source

Tunable Response of Silica-Gold Nanoparticles for Improved Efficiency in Photothermal Therapy. [PDF]

open access: yesNanomaterials (Basel)
Motilla-Montes JR   +4 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

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