Results 131 to 140 of about 10,525,256 (347)
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Entornos virtuales y formación flexible
Tecnología en Marcha, 2004 La enseñanza formal y, fundamentalmente, la enseñanza superior ‘convencional’, sea presencial o a distancia, se transforma y evoluciona hacia modalidades de aprendizaje abierto, donde se produce una oferta educativa flexible.
Jesús Salinas-Ibáñez
doaj
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Determinación teórica de la histéresis eléctrica en materiales compuestos ferroeléctricos [PDF]
, 2013 En este trabajo se establecen relaciones entre la histéresis eléctrica macroscópica y el comportamiento de las fases constitutivas en materiales compuestos ferroeléctricos con microestructuras complejas y sometidos a historias de carga arbitrarias.
Idiart, Martín Ignacio
core
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
FEBS Letters, EarlyView.The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber +7 more
wiley +1 more source
El profesorado de apoyo en los centros ordinarios. Nuevas funciones, nuevas contradicciones.
Educatio Siglo XXI, 2012 El presente artículo desarrolla las funciones que la actual normativa señala para el profesorado de apoyo, especialista en la atención del alumnado con necesidades educativas especiales, en los centros ordinarios y analiza las diferentes contradicciones ...
Asunción Moya Maya
doaj
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source