Results 131 to 140 of about 49,978 (267)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Materiales Magnéticos. Materiales magnéticos duros: hexaferritas

open access: yes
En este Trabajo de Fin de Grado se presentan todos los pasos realizados para alcanzar el objetivo de sintetizar y caracterizar un material magnéticamente duro, la hexaferrita de estroncio. Con este propósito, se realiza una revisión bibliográfica para comprender los conceptos clave sobre el magnetismo en la materia, destacando aquellos más ...
openaire   +1 more source

Influence of the TiO<sub>2</sub> Precursor Phase on the Properties and Photoelectrooxidation Performance of Black TiO<sub>2</sub>-Impregnated Electrodes for Acetaminophen Degradation. [PDF]

open access: yesMolecules
Solarte-Ferro D   +8 more
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Mn(III)-O-Ce(IV) as a Surrogate for Highly Reactive Non-Heme Mn(IV)═O Species Supported by Benzimidazole-Based Ligand. [PDF]

open access: yesInorg Chem
Gupta S   +11 more
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

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