Results 171 to 180 of about 10,525,256 (347)
, 2012 Objeto de aprendizaje: Presentación multimediaEste recurso educativo habla acerca de los materiales que se deben analizar y su clasificación iniciando con los polímeros, las cerámicas, los materiales compuestos y finalmente los semiconductores.This ...
Hernández Leal, John Ivan
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Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
, 2014 Presentación que se encarga de explicar los materiales compuestos y sus propiedades, así como también su origen y algunos aspectos a tener en cuenta sobre los mismos.Un material compuesto es la mezcla de dos o más materiales de diferentes familias, pero ...
Vergara Pérez, Oswaldo Enrique
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Matrices poliméricas para materiales compuestos
, 2010 Materiales compuestos. Introducción a la importancia de los materiales compuestos y el papel principal de la matriz. Funciones de la matriz. Tipos de matrices en materiales compuestos: cerámicas (CMCs), metálicas (MMCs) y poliméricas (PRF).https ...
Balart, Rafael
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M<sub>x</sub>C<sub>y</sub>-Type Nanocarbide Crystallization in CrMnFeCoNi, CrMnFeCoNiV<sub>0.5</sub>, and CrMnFeCoNiMo<sub>0.5</sub> HEAs Manufactured Through Powder Metallurgy. [PDF]
Nanomaterials (Basel)Garcia AM +10 more
europepmc +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source