Results 81 to 90 of about 50,783 (275)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Frontiers in PsychologyIntroductionAdolescent materialism has been increasingly associated with a range of psychological health issues. This study explored the central components of materialism and their associations with social support using an undirected partial-correlation ...
Sen Li, Ruosi Gao, Xiang Li, Tianran Li
doaj +1 more source
Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2016 The theory of inhomogeneous analytic materials is developed. These are materials where the coefficients entering the equations involve analytic functions. Three types of analytic materials are identified. The first two types involve an integer p .
openaire +3 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
ACME, 2019 Dialectical materialism, we argue is a philosophical praxis that guided Marx’s critique of capitalist political economy. In this article, we have attempted a self-critique of human geography by explicating that dialectical materialism has been largely ...
Ipsita Chatterjee, Waquar Ahmed
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Journal of Nanoscience and Nanotechnology, 2002 The current review article attempts to cover the field of nanoporous materials, thereby materials with voids of the order of 1 nm to 100 nm or even larger. Concepts, that have an effect on a more general basis, are introduced and the common features among the different classes of nanoporous materials are demonstrated enabling understanding their ...
Polarz, Sebastian, Smarsly, Bernd
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Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Self-compassion, the ‘quiet ego’ and materialism
Heliyon, 2018 The research is an investigation of self-compassion and materialism. Self-compassion is when an individual has a caring, non-judgmental view of the self.
David C. Watson
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Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source