Results 121 to 130 of about 400,850 (345)

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

"We produce under this sky": making organic wine in a material world [PDF]

open access: yes, 2012
This thesis explores the role of living and non-living materials as active agents in the processes of making and marketising organic wines in Northern Italy.
Krzywoszynska, Anna
core  

The Dressed Body, Material and Technology: Rethinking the Hijab through Sartorial Sociology [PDF]

open access: yes, 2018
This article explores the opportunities provided for dress and fashion studies by an analytical focus on garments through a number of disciplinary and conceptual lenses.
Almila, Anna-Mari
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

What Is the Bioeconomy? A Review of the Literature

open access: yes, 2016
The notion of the bioeconomy has gained importance in both research and policy debates over the last decade, and is frequently argued to be a key part of the solution to multiple grand challenges.
Markus M. Bugge   +2 more
semanticscholar   +1 more source

Arquivos e Edições Digitais

open access: yesMatLit, 2013
Brief introduction to seven digital archives: Rossetti Archive, Dickinson Electronic Archives, The William Blake Archive, Radical Scatters, Arquivo Pessoa, Espólio Fernando Pessoa and Samuel Beckett Digital Manuscript Project.
Manuel Portela, Matheus de Brito
doaj  

WRITING UTOPIA NOW: Utopian Poetics In The Work Of Theresa Hak Kyung Cha [PDF]

open access: yes, 2020
This thesis examines Theresa Hak Kyung Cha’s DICTEE (1982), Audience Distant Relative (1977) and Reveillé dans la Brume (Awakened in the Mist) (1977). The premise of the thesis is an exploration of the various ways in which these works both perform and ...
Willow, S., Willow, S.
core  

‘So people know I'm a Sikh’: Narratives of Sikh masculinities in contemporary Britain [PDF]

open access: yes, 2014
This article examines British-born Sikh men's identification to Sikhism. In particular, it focuses on the appropriation and use of Sikh symbols amongst men who define themselves as Sikh. This article suggests that whilst there are multiple ways of ‘being’
Ballantyne T.   +4 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

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