Results 91 to 100 of about 9,777,016 (318)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Study of Physically Transient Insulating Materials as a Potential Platform for Transient Electronics and Bioelectronics [PDF]
Controlled degradation and transiency of materials is of significant importance in the design and fabrication of degradable and transient biomedical and electronic devices and platforms.
KESSLER, Michael R. +13 more
core +1 more source
Evaluating Makiwara Punching Board Performance
No studies quantifying the impact characteristics of makiwara boards are available in the published literature. Logically, an initial step in determining the validity of the makiwara to develop karate technique would be to assess the mechanical ...
Paul K. Smith +2 more
doaj
This paper summarizes the practical experience gained in the Federal Republic of Germany in connection with the development and implementation of a national reference system. The National Reference System is set forth in: 1. the New Calibration Act 1986 (Neufassung des Eichgesetzes vom 22. Februar 1985. Bundesgesetzblatt 1985, Teil I, 410-422); 2.
openaire +3 more sources
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Building Blocks Incorporating Waste Materials Bound with Bitumen
This paper described an investigation and evaluation which was carried out in the United Kingdom-UK, on the properties of masonry building block materials that incorporate waste materials, namely: steel slag, crushed glass, coal fly ash, rice husk ash ...
Thanaya I.N.A.
doaj
Biophysical approaches for studying viral entry
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Technology and green measures to a resilient architecture
The scope of the effects that climate change implies in different territories requires a rethink of the current approach to the city’s design. The new orientation is directed towards resilient design (from Latin to resilient) that is sustainable, agile ...
Santina Di Salvo
doaj +1 more source
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source

