Results 71 to 80 of about 6,341,126 (268)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Technology and green measures to a resilient architecture
Agathón, 2017 The scope of the effects that climate change implies in different territories requires a rethink of the current approach to the city’s design. The new orientation is directed towards resilient design (from Latin to resilient) that is sustainable, agile ...
Santina Di Salvo
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Una herramienta para la selección automatizada de aceros en el contexto de la Ingeniería Mecánica [PDF]
Ingeniería Mecánica, 2010 El diseño de Ingeniería de un producto o componente constituye una actividad difícil, compleja y multidisciplinaria, enfocada a la resolución de problemas.
L. Dumitrescu +3 more
doaj
Agathón, 2017 The article declines the terms of architecture and nature according to three different meanings: architectural shapes that are similar to natural ones because they are inspired by nature; forms characterized by the materials that nature offers in ...
Alberto Sposito
doaj +1 more source
The northeast materials database for magnetic materials
Nature CommunicationsThe discovery of magnetic materials with high operating temperature ranges and optimized performance is essential for advanced applications. Current data-driven approaches are limited by the lack of accurate, comprehensive, and feature-rich databases.
Suman Itani, Yibo Zhang, Jiadong Zang
openaire +3 more sources
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Modes and moods of “Slave Anastácia,” Afro-Brazilian saint
Journal de la Société des Américanistes, 2018 Agency activated through exchanges with saints is not simply present or absent. Rather it is emergent, depending on the mode of saints’ material and social configurations, and the mood evoked by a specific saint’s manifestation.
Paul Christopher Johnson
doaj +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source