Results 71 to 80 of about 767,187 (168)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Evaluating Makiwara Punching Board Performance
Revista de Artes Marciales Asiáticas, 2012 No studies quantifying the impact characteristics of makiwara boards are available in the published literature. Logically, an initial step in determining the validity of the makiwara to develop karate technique would be to assess the mechanical ...
Paul K. Smith +2 more
doaj
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Building Blocks Incorporating Waste Materials Bound with Bitumen
Civil Engineering Dimension, 2010 This paper described an investigation and evaluation which was carried out in the United Kingdom-UK, on the properties of masonry building block materials that incorporate waste materials, namely: steel slag, crushed glass, coal fly ash, rice husk ash ...
Thanaya I.N.A.
doaj
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Technology and green measures to a resilient architecture
Agathón, 2017 The scope of the effects that climate change implies in different territories requires a rethink of the current approach to the city’s design. The new orientation is directed towards resilient design (from Latin to resilient) that is sustainable, agile ...
Santina Di Salvo
doaj +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Una herramienta para la selección automatizada de aceros en el contexto de la Ingeniería Mecánica [PDF]
Ingeniería Mecánica, 2010 El diseño de Ingeniería de un producto o componente constituye una actividad difícil, compleja y multidisciplinaria, enfocada a la resolución de problemas.
L. Dumitrescu +3 more
doaj
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source