FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
High-throughput screening of room temperature active Peltier cooling materials in Heusler compounds [PDF]
, 2022 Huifang Luo +5 more
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FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Ceramic composite materials for working at high temperatures
Construction, materials science, mechanical engineering, 2010 A technology has been developed for the manufacture of powder composite materials for the production of a flame tube of aircraft engines. The tests performed showed high heat resistance of materials, if subjected to annealing after formation.
Bol'shakov, V. I. +8 more
openaire +1 more source
Numerical simulation of crack propagation in ceramic materials at high temperature
, 2018 Fengshan Han, Xinli Wu, Zhongliang Cui
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Ytterbium Silicide (YbSi2): A Promising Thermoelectric Material with a High Power Factor at Room Temperature (Phys. Status Solidi RRL 2/2018) [PDF]
, 2018 Sora‐at Tanusilp +6 more
openalex +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
107 Study on High Polymer Materials by Dynamic Load in Low Temperature
, 2009 Daisuke SASAOKA, Tsutomu EZUMI
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Characterization of AlN-based Ceramic Composites for Use as Millimeter Wave Susceptor Materials at High Temperature: High Temperature Thermal Properties of AlN:Mo with 0.25% to 4.0% Mo by Volume [PDF]
, 2019 Brad W. Hoff +6 more
openalex +1 more source