Results 31 to 40 of about 551,340 (264)

Formation of high-aspect-ratio nanocavity in LiF crystal using a femtosecond X-ray free-electron laser pulse

Nature Communications
Recent research and development into the formation of nanoscale channels as a central component of nanofluidic biochip systems revolutionized the biological and chemical fields.
Sergey S. Makarov, Vasily V. Zhakhovsky, Sergey Yu. Grigoryev, Petr Chuprov, Tatiana A. Pikuz, Nail A. Inogamov, Victor A. Khokhlov, Yuri V. Petrov, Evgeniy A. Perov, Vadim Shepelev, Takehisa Shobu, Aki Tominaga, Ludovic Rapp, Saulius Juodkazis, Mikako Makita, Motoaki Nakatsutsumi, Thomas R. Preston, Karen Appel, Zuzana Konopkova, Valerio Cerantola, Erik Brambrink, Jan-Patrick Schwinkendorf, István Mohacsi, Vojtech Vozda, Vera Hajkova, Tomas Burian, Jaromir Chalupsky, Libor Juha, Norimasa Ozaki, Ryosuke Kodama, Ulf Zastrau, Andrei V. Rode, Sergey A. Pikuz   +32 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

High-Temperature Annealing Effects on Atomically Thin Tungsten Diselenide Field-Effect Transistor

Applied Sciences, 2022
Two-dimensional (2D) material-based devices are expected to operate under high temperatures induced by Joule heating and environmental conditions when integrated into compact integrated circuits for practical applications.
Muhammad Atif Khan, Muhammad Qasim Mehmood, Yehia Massoud   +2 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Synchronized Full-Field Strain and Temperature Measurements of Commercially Pure Titanium under Tension at Elevated Temperatures and High Strain Rates

Metals, 2021
Understanding the mechanical behavior of materials at extreme conditions, such as high temperatures, high strain rates, and very large strains, is fundamental for applications where these conditions are possible. Although tensile testing has been used to
Guilherme Corrêa Soares, Mikko Hokka
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Effect of Expanded Perlite Aggregate Plaster on the Behavior of High-Temperature Reinforced Concrete Structures

Buildings, 2023
Polyurethane-based materials, which are widely used in exterior cladding, pose a great risk for buildings because they can easily catch fire at temperatures as low as 50–65 °C.
İsmet Ulusu, Aslıhan Kurnuç Seyhan
doaj   +1 more source

Behavior Of Materials At High Temperatures [PDF]

2004 Annual Conference Proceedings, 2020
Comment: 9 ...
openaire   +2 more sources