Results 101 to 110 of about 11,945,342 (367)

A Review on the Bulk and Surface Chemistry of Iron in Atmospherically-relevant Systems Containing Humic Like Substances (HULIS) [PDF]

open access: yes, 2015
As the fourth most abundant element by mass in the Earth’s crust, iron is ubiquitous and its chemistry is rich and interdisciplinary in nature. This review synthesizes the current state of knowledge of iron chemistry in multicomponent atmospheric ...
Al-Abadleh, Hind A.
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Characterization and densification of defect pyrochlore oxide powders ABi2Ta5O16 (A=Na, Tl)

open access: yesHeliyon, 2019
Defect pyrochlore oxide powders ABi2Ta5O16, in the pseudo-binary systems BiTaO4–ATa3O8 (A = Na, Tl), were prepared by solid state method. The structural study showed that all oxides crystallize in a cubic system with the space group Fd3m, the lattice ...
O. Ait Sidi Ahmed   +7 more
doaj   +1 more source

Materials chemistry: Design, Synthesis and Functionality [PDF]

open access: yes, 2017
The need to synthesise new materials is driven by the need for materials with specific functionality, which is in turn driven by the intended final application.
Hix, Gary B.
core  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Optical studies of the solution phase reduction and stabilization of indigo tetrasulfonate in polyelectrolyte complexes

open access: yesHeliyon, 2017
Ultraviolet-visible (UV-vis) and fluorescence spectroscopy have been used to characterize the polyelectrolyte complexes (PECs) formed when potassium indigo tetrasulfonate (ITS) interacts with poly diallydimethylammonium chloride (PDADMAC) through ...
Becca Hoene, Dion Rivera
doaj   +1 more source

Transition metal oxides using quantum Monte Carlo

open access: yes, 2007
The transition metal-oxygen bond appears prominently throughout chemistry and solid-state physics. Many materials, from biomolecules to ferroelectrics to the components of supernova remnants contain this bond in some form.
  +11 more
core   +1 more source

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