Results 91 to 100 of about 10,926,875 (269)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Materials Engineering of Violin Soundboards by Stradivari and Guarneri. [PDF]

open access: yesAngew Chem Int Ed Engl, 2021
Su CK   +29 more
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

A materials approach to the redesign of Lacrosse helmets

open access: yes, 1988
Thesis (B.S.)--Massachusetts Institute of Technology, Dept. of Materials Science and Engineering, 1988.Includes bibliographical references.by Robert I.
Park, Robert I. (Robert Inyeung)
core  

Retracted: Nanoscale Characterization and Impurities of Fused Silica Optical Surfaces

open access: yesAdvances in Materials Science and Engineering, 2023
Advances in Materials Science and Engineering
doaj   +1 more source

The ferroelectric photo ground state of SrTiO3: Cavity materials engineering. [PDF]

open access: yesProc Natl Acad Sci U S A, 2021
Latini S   +6 more
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Materials Evaluation and Engineering, Inc.: Forensic Engineering Investigations

open access: yes, 2000
This website from Materials Evaluation and Engineering, Inc., which specializes in the analysis of product failures, points out that materials engineering is useful in product failure analysis because many products fail due to materials problems.

core  

Retracted: Simulation Analysis of External Damage and Repair of the Gas Transmission Pipeline

open access: yesAdvances in Materials Science and Engineering, 2023
Advances in Materials Science and Engineering
doaj   +1 more source

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