Results 101 to 110 of about 1,676,767 (268)
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Composite Materials Engineering Graduating Class Photograph: 2012
This is a class photograph of the Composite Materials Engineering Graduating Class of 2012 at Winona State University. The students in the photograph are: Richard Anfinsen, Austin Erdenberger, Ryan Foley, Ben Gerjets, Emily Hammel, Benjamin Malcheski ...
Composite Materials Engineering Department-Winona State University
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Composite Materials Engineering Graduating Class Photograph: 2021
This is a class photograph of the Composite Materials Engineering Graduating Class of 2021 at Winona State University. The students in the photograph are: Zachary Alboreo, Nathanael Antwi, Sean Coleman, Casey Cooper, Lucas A.
Composite Materials Engineering Department-Winona State University
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Advances in Materials Science and Engineering
doaj +1 more source
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Composite Materials Engineering Graduating Class Photograph: 2005
This is a class photograph of the Composite Materials Engineering Graduating Class of 2005 at Winona State University. The students in the photograph are: Greg Applewhite, Michael Brennan, Ronald Dehn, Robert Fagerlund, John Geldernick, Kevin Kottke ...
Composite Materials Engineering Department-Winona State University
core
Advances in Materials Science and Engineering
doaj +1 more source
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Advances in Materials Science and Engineering
doaj +1 more source
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source

