Results 51 to 60 of about 830,862 (265)

Risk Assessment of Sari Fatemeh Zahra Hospital Using Failure Mode Effect Analysis, Individualized Rapid Assessment Tool, and Preliminary Hazard Analysis

open access: yesJournal of Mazandaran University of Medical Sciences, 2018
Background and purpose: Identification of risk in hospital waste management have a major role in reducing the cost of surplus and preventing the spread of diseases.
Tayebeh Mansouri   +4 more
doaj  

Presenting a Semi-quantitative Model Based on the Resiliency Engineering Management Commitment Index in Assessing the Level of Preparedness Against Emergency Situations of Hospitals in a Fuzzy Environment (Case Study: Selected Faraja Hospitals in 2021) [PDF]

open access: yesMuhandisī-i bihdāsht-i ḥirfah/ī, 2023
Background and Objective: The main index in resilience engineering is the management commitment index. This study implemented a semi-quantitative risk assessment method based on the fuzzy hierarchical analysis method for the management commitment index ...
Rasoul Jannaty
doaj  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Exploring the Components of Green Hospitals Through an Accreditation-Based Approach: A Qualitative Study [PDF]

open access: yesJournal of Mazandaran University of Medical Sciences
Background and purpose: Defining the components of a green hospital has a significant impact on the performance of healthcare systems and the achievement of sustainable health goals. However, the conceptualization of these components remains complex, and
Ghasem Abedi   +2 more
doaj  

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Hospital waste management in nonteaching hospitals of Lucknow City, India

open access: yesJournal of Family Medicine and Primary Care, 2014
Objective: To assess hospital waste management in nonteaching hospitals of Lucknow city. Materials and Methods: A cross-sectional, descriptive study was conducted on the staffs of nonteaching hospitals of Lucknow from September 2012 to March 2013.
Manish Kumar Manar   +2 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

Optimizing Pathological Examination Cost Control Through Process Management Information Systems: A Mixed-Methods Study

open access: yesRisk Management and Healthcare Policy
Qin Huang,1,2 Wei Jiang,1,2 Ying He,1,2 Wei Wang,1,2 Bo Song1,2 1Department of Pathology, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, People’s Republic of China; 2Key Laboratory of Birth Defects and Related Diseases of ...
Huang Q, Jiang W, He Y, Wang W, Song B
doaj  

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