Results 61 to 70 of about 830,862 (265)

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

Molecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna, Jodie Hay, Michael W. Moles, Lucy Clarke, Jennifer Cassels, Alison Sefcick, Alison M. McCaig, Heather G. Jørgensen, Alison M. Michie   +8 more
wiley   +1 more source

PENILAIAN BAHAN BERBAHAYA BERACUN PADA LABORATORIUM RADIOLOGI RSUD BANGIL KABUPATEN PASURUAN

The Indonesian Journal of Occupational Safety and Health, 2018
The consequence of activity in hospital is to produce toxic material waste (B3). So, description of B3 in the hospital was needed. The objective of this research was to identify the hazards in each stage in waste management of Liquid Hazardous and Toxic (
Frans Salesman, Umi Farida
doaj   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

Understanding occupational health challenges in managing hospital solid waste in Zimbabwe: a critical review

Discover Public Health
Industrialisation and service provision expose involved people to occupational health risks, including solid waste workers. In Zimbabwe, many concerns focus on occupational health risks affecting workers in industries, giving little attention to those ...
Steven Jerie, Timothy Vurayayi Mutekwa, Tapiwa Shabani, Takunda Shabani, Amato Chireshe   +4 more
doaj   +1 more source

Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up

Molecular Oncology, EarlyView.
This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani, Laura Mariën, Caro De Weerdt, Sanne Wouters, Laure‐Anne Teuwen, Hans Prenen, Katleen Janssens, Timon Vandamme   +7 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Waste Management in Selected Hospitals of Teheran University of Medical Sciences: Staff Awareness and Hospital Performance -2012

بیمارستان, 2014
Background: Hospital waste is one of the environmental problems .Ignoring the proper management of these wastes can lead to outbreak of diseases and epidemics which threat the public health and rise high costs as a result.
E Zeraatkar, H Rahmani, M Ghazi Asgar, J Saeid Pour, S Azami, A Aryankhesal, M pakdaman   +6 more
doaj  

Clinical Evaluation of Dural (Spinal) Membrane Repair Materials

Zhongguo yiliao qixie zazhi
ObjectiveTo select high-quality and cost-effective dural (spinal) membrane repair materials, in order to reduce the cost of consumables procurement, save medical insurance funds, and optimize hospital operation and management.
Linling ZHANG, Chang SU, Tingting DONG, Kun ZHENG   +3 more
doaj   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

COVID-19 pandemic management at a hospital in Somalia: A qualitative study

Journal of Public Health Research
Background COVID-19 pandemic management in the hospitals is important for the prevention practices of health staff. Studies assessing COVID-19 pandemic management in Somali hospitals are limited.
Abdullahi Ibrahim Janay, Belgin Unal, Bulent Kilic   +2 more
doaj   +1 more source