Results 141 to 150 of about 416,348 (303)

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Innovative bridge design/construction techniques to expedite construction

, 2005
Title from cover.; "August 2005."; Includes bibliographical references (p. 37).; Final report.; Performed by University of Cincinnati, Dept. of Civil and Environmental Engineering, sponsored by Ohio Dept.
Miller, Richard A., P.E., University of Cincinnati. Dept. of Civil and Environmental Engineering.   +1 more
core  

Design of Engineered Living Materials for Martian Construction

arXiv admin note: text overlap with arXiv:2406 ...
Rokaya, Nisha, Carr, Erin C., Wilson, Richard A., Jin, Congrui   +3 more
openaire   +2 more sources

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Construction materials inventory of Cowley County, Kansas

, 1978
Kansas Department of Transportation, Engineering Services Department, Planning and Development Department Prepared in Cooperation with the U.S. Department of Transportation, Federal Highway Administration.

core  

Construction materials and their processing

The special issue contains articles that are dedicated to the analysis of the latest research results in the area of structural and functional materials and their processing and synthesis technologies, including methods of their applications in machinery

core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Optimizing Work Zone Zipper Merge Using Federated Driving Simulators [PDF]

MoDOT project # TR202009Several Departments of Transportation have implemented the zipper merge to counter the issues of wasted capacity and queue jumping that surface at early merge work zones. This project researched four issues related to zipper merge
Edara, Praveen, University of Missouri--Columbia. Department of Civil and Environmental Engineering, Sun, Carlos, Canfield, Casey, Anowar, Sabreena   +4 more
core  

Author Correction: Straightforward construction of functionalized γ-lactams via conjugated-engineered covalent organic framework photocatalysed cascade reactions. [PDF]

Nat Commun
Lin X, Li J, Zheng J, Cai X, Wang L, Sa R, Si C, Jiang D, Kang Y, Wang J, Yamauchi Y, Yuan Z.   +11 more
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source