Results 151 to 160 of about 1,326,374 (407)
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Engineering properties of bio-inspired cement mortar containing seashell powder [PDF]
Cement mortar is a semi liquid formed by a composite of cement, sand and water. Generally, cement mortar is used as a medium for bricks laying in construction.
Md. Tahir, Mahmood+2 more
core
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche+8 more
wiley +1 more source
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner+6 more
wiley +1 more source
Composite materials for rail transit systems [PDF]
The potential is explored for using composite materials in urban mass transit systems. The emphasis was to identify specific advantages of composite materials in order to determine their actual and potential usage for carbody and guideway structure ...
Griffin, O. Hayden, Jr.+2 more
core +1 more source
Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva+5 more
wiley +1 more source
Materials Based on Chitosan and Polylactide: From Biodegradable Plastics to Tissue Engineering Constructions [PDF]
Tatiana S. Demina+2 more
openalex +1 more source
Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo+11 more
wiley +1 more source
Effect of biological shells aggregate on the mechanical properties and sustainability of concrete
The recycling bio-waste shells problem has grown more and more serious in recent years and many efforts have been made to solve this problem. One possible solution is to put these bio-shells into concrete and recycle them as building materials using the ...
Xianpeng Wang+6 more
doaj +1 more source
Internationalization of the knowledge on construction materials of structutral engineers
Resumen del trabajo presentado a la IV International Conference on Structural Engineering: Education Without Borders, celebrada en Madrid (España) del 20 al 22 de junio de 2018.
Roig-Flores, M.+2 more
openaire +1 more source