Results 61 to 70 of about 416,348 (303)

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Synthesis of MnO2–CuO–Fe2O3/CNTs catalysts: low-temperature SCR activity and formation mechanism

Beilstein Journal of Nanotechnology, 2019
MnO2–CuO–Fe2O3/CNTs catalysts, as a low-dimensional material, were fabricated by a mild redox strategy and used in denitration reactions. A formation mechanism of the catalysts was proposed. NO conversions of 4% MnO2–CuO–Fe2O3/CNTs catalyst of 43.1–87.9%
Yanbing Zhang, Lihua Liu, Yingzan Chen, Xianglong Cheng, Chengjian Song, Mingjie Ding, Haipeng Zhao   +6 more
doaj   +1 more source

The Influence of Cl- and Ca2+ on the Passive Film of 00Cr10MoV Steel in Simulated Concrete Solution

International Journal of Electrochemical Science, 2017
The influence of Cl- and Ca2+ on the naturally growing passive film of a new, alloyed stainless steel with 10% Cr and 0% Ni was investigated by electrochemical impedance spectroscopy, Mott-Schottky curves, X-ray photoelectron spectroscopy (XPS), and ...
Jinyang Jiang, Danqian Wang, Hong-yan Chu, Han Ma, Jinjie Shi, Wei Sun   +5 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

A systematical review of 3D printable cementitious materials

, 2019
3D printing, or additive manufacturing, is a technology which adopts layer-by-layer additive deposition process to build three-dimensional objects.
Leong, Kah Fai, Qian, Ye, Tan, Ming Jen, Qian, Shunzhi, Lu, Bing, Weng, Yiwei, Li, Mingyang   +6 more
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Tentative field engineering index for rocks: Technical manuscript

, 2020
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Construction Engineering Research Laboratory (U.S.);
core  

Resistance Properties to Chloride Ingress of Standard-Cured Concrete Made with an Admixture Incorporating Rich SiO2 and Al2O3

International Journal of Concrete Structures and Materials, 2020
In regions where the concrete structures are exposed to a salty environment, the concrete requires high resistance to chloride-ion penetration. To achieve higher resistance against chloride ingress, a pozzolanic admixture incorporating a high volume of ...
Koichiro Yamato, Akira Sasaki, Takayasu Ito, Isamu Yoshitake   +3 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source