Results 71 to 80 of about 1,418,690 (312)

The performance of polyurethane grout to stabilise hemic peat [PDF]

, 2020
Peat has always considered as a challenging ground for any form of construction due to its engineering characteristics such as high short-term settlement, prolonged long term post construction settlement and high natural moisture content exceedingly ...
Abdurahman, Mohamad Niizar
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Resistance Properties to Chloride Ingress of Standard-Cured Concrete Made with an Admixture Incorporating Rich SiO2 and Al2O3

International Journal of Concrete Structures and Materials, 2020
In regions where the concrete structures are exposed to a salty environment, the concrete requires high resistance to chloride-ion penetration. To achieve higher resistance against chloride ingress, a pozzolanic admixture incorporating a high volume of ...
Koichiro Yamato, Akira Sasaki, Takayasu Ito, Isamu Yoshitake   +3 more
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Synthesis of MnO2–CuO–Fe2O3/CNTs catalysts: low-temperature SCR activity and formation mechanism

Beilstein Journal of Nanotechnology, 2019
MnO2–CuO–Fe2O3/CNTs catalysts, as a low-dimensional material, were fabricated by a mild redox strategy and used in denitration reactions. A formation mechanism of the catalysts was proposed. NO conversions of 4% MnO2–CuO–Fe2O3/CNTs catalyst of 43.1–87.9%
Yanbing Zhang, Lihua Liu, Yingzan Chen, Xianglong Cheng, Chengjian Song, Mingjie Ding, Haipeng Zhao   +6 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

A way to reuse petrochemical wastes through the partial substitution of cement by spent cracking catalyst and its effect on cement pastes

Scientific Reports
This study examined the recycling of spent catalyst from Fluid Catalytic Cracking (FCC) process derived from Polish petroleum industry in cementitious materials.
Paweł Niewiadomski, Michał Cisiński, Barbara Batog, Agnieszka Chowaniec-Michalak, Elżbieta Janowska-Renkas, Martyna Nieświec   +5 more
doaj   +1 more source

Effect of a novel negative temperature early-strength agent in improving concrete performance under varying curing temperatures

Case Studies in Construction Materials
This study investigates the effect of a novel negative temperature early-strength agent (NEA) in enhancing concrete performance under varying curing temperatures, with a discussion on the underlying mechanism through analysis of hydration products and ...
Yasong Zhao, Yuxin Zhao, Zhaohui Zhu, Gaofeng Chen, Huixia Wu, Cheng Liu, Jianming Gao   +6 more
doaj   +1 more source