Results 91 to 100 of about 373,580 (313)

Insights into the corrosion resistance of Cr-Mo alloy reinforcing steel in simulated pore solution and real seawater sea-sand concrete: A preliminary study

Case Studies in Construction Materials
Corrosion of steel bars embedded in reinforced concrete structures considerably reduces the service life and even causes early failure of the structure.
Zhongyi Xin, Le Guo, Fengjuan Wang, Qi Luo, Liguo Wang, Huande Chen, Zhiyong Liu, Jinyang Jiang   +7 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Modern design, construction and maintenance of composite steel-concrete structures : Australian experiences

, 2007
Modern design, construction innovation and maintenance issues have been extensively utilised for composite steel-concrete building structures in Australia.
Uy, Brian, Mendis, Priyan, Ngo, Tuan
core  

Quantitative solution on dosage of repair agent for healing of cracks in materials: short capsule model vs. two-dimensional crack pattern

Science and Engineering of Composite Materials, 2011
Cracks are vitally detrimental to the load-bearing capacity of materials and further to the durability and service-life of various structures. Crack-repairing technology via embedded capsules with repair agent is becoming a promising approach to sustain ...
Lv Zhong, Chen Huisu, Yuan Haifeng
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Special Issue “Research and Development of Building Materials Based on Industrial Waste”

, 2023
This Special Issue, titled “Research and Development of Building Materials Based on Industrial Waste”, is focused on the preparation and description of the properties of new building materials based on industrial waste that are to be used in ...
Vojtěch Václavík
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Syntheses, characterization, crystal structures and antibacterial activity of pyridine containing hydrazones

Acta Chimica Slovenica
Three new hydrazone compounds derived from 3-pyridinecarboxaldehyde with hydrazides, and two new hydrazone compounds derived from nicotinohydrazide with aldehydes were prepared and characterized by elemental analyses, IR and 1H NMR spectroscopy, and ...
De-Jun Meng, Yan-Chun Hou, Ning Wang, Ming-Jie Ding, Yin-Feng Li   +4 more
doaj   +1 more source