Results 101 to 110 of about 1,418,690 (312)
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
CEC research activities for the period 2003-2005 [PDF]
, 2005 The Civil Engineering Research Center of the University of Minho will carry out research at an internationally recognised standard of excellence in the following areas: - Construction Materials, dealing with achieving sustainable materials focussing in
Barros, Joaquim A. O., Correia, A. Gomes
core
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Summary of tower designs for large horizontal axis wind turbines [PDF]
Towers for large horizontal axis wind turbines, machines with a rotor axis height above 30 meters and rated at more than 500 kW, have varied in configuration, materials of construction, type of construction, height, and stiffness.
Frederick, G. R., Savino, J. M.
core +1 more source
Innovative all composite multi-pultrusion truss system for stressed arch deployable shelters [PDF]
, 2007 Trusses are one of the successful structural forms that have been utilised, at extended scale, since the nineteen century. Fibre composite materials are relatively new to civil engineering applications. The increased interest in using composites in civil
Aravinthan, T. +3 more
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Mechanics of a Plant in Fluid Flow
, 2019 Plants live in constantly moving fluid, whether air or water. In response to the loads associated with fluid motion, plants bend and twist, often with great amplitude. These large deformations are not found in traditional engineering application and thus
Gosselin, Frederick P.
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Наука и техника, 2005 The paper analyses foreign experience in application of modem geo-synthetic materials in construction. Data are presented about the modem types of geo-synthetic materials applied abroad and in Belarus.Standard constructions of the used geo-synthetics and technological schemes of their application in construction of water development, water-protecting ...
openaire +2 more sources
Project of building a restaurant in Kiev to study the foundation [PDF]
, 2019 У проекті будівлі ресторану в Києві з дослідженням фундаменту запропоновано тривимірне планування та інженерно-конструкторські рішення. Розрахунок основних несучих конструкцій. Проведено термотехнічний розрахунок огороджувальних конструкцій.
Tekin, Erdal, Текін, Ердал
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source