Results 31 to 40 of about 59,884 (215)
Plastics in the US: toward a material flow characterization of production, markets and end of life
Environmental Research Letters, 2020 Managing plastics has become a focal issue of the Anthropocene. Developments in plastic materials have made possible many of the technologies and conveniences that define our modern life.
Martin C Heller +2 more
doaj +1 more source
Fabrication and Biodegradability of Starch Cell-Plastics as Recyclable Resources
Applied Sciences, 2021 Recently, cell-plastics, which are composed of unicellular green algal cells and biodegradable compounds as ingredients and fillers, have been suggested as carbon-recyclable materials instead of petroleum-based plastics.
Akihito Nakanishi +7 more
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Computational Rheology with Integral Constitutive Equations
Applied Rheology, 1999 Computational rheology deals with the formulation and solution of constitutive equations for non-Newtonian materials. From these the emphasis is put on polymeric materials, which exhibit both viscous and elastic behaviour in flow and deformation.
Mitsoulis Evan
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Living plastics from plasticizer-assisted thermal molding of silk protein
Nature CommunicationsThe pursuit of materials, particularly plastics, with a minimal ecological footprint throughout their circular lifecycle, is crucial for advancing sustainable materials development.
Yushu Wang +12 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Functional carbon materials from waste plastics: synthesis and applications
Sustainable Carbon MaterialsThe global accumulation of waste plastics has led to severe environmental pollution, posing a serious threat to ecosystems. Conventional disposal methods, such as landfilling, mechanical recycling, and incineration, remain limited by low conversion ...
Jin Yuan +4 more
doaj +1 more source