Results 51 to 60 of about 5,093,415 (207)

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Catalogació de l’impacte ambiental de plàstics. Materials convencionals [PDF]

open access: yes, 2015
Els plàstics són un tipus de materials que presenten múltiples aplicacions en diversos camps. Des del seu descobriment, la seva demanda no ha fet més que incrementar gràcies a les seves excel·lents propietats.
Miernau Raurell, Mònica
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

The role of biodegradable plastics in a sustainable economy: Progress and challenges

open access: yesCleaner Engineering and Technology
The widespread use of plastics has resulted in significant environmental challenges, including pollution, landfill accumulation, and harm to ecosystems and human health.
Tina Kegl, Yee Van Fan, Lidija Čuček
doaj   +1 more source

Сhoice of materials for producing dimensionally stable load-carrying structures

open access: yesВестник Самарского университета: Аэрокосмическая техника, технологии и машиностроение, 2018
The article deals with the problems of choosing materials for producing dimensionally stable load-carrying structures of space optical electronic complexes.
V. E. Bitkin   +2 more
doaj   +1 more source

ESTRUCTURA I PROPIETATS DELS MATERIALS PLÀSTICS (2n examen parcial)

open access: yes, 2010
Examen d'Estructura i propietats dels materials ...
Antunes, Marcelo de Sousa Pais
core  

Dràstics amb els plàstics [PDF]

open access: yes, 2019
Programa Metropolità d'Educació per a la SostenibilitatLa proposta educativa s'adreça a alumnes de segon cicle d'ESO i s'emmarca en els projectes de servei comunitari, que es complementen amb el suport d'altres àmbits, com el lingüístic, l'artístic, el ...
Àrea Metropolitana de Barcelona
core  

Effect of terahertz irradiation on DNA damage repair in living cells

open access: yesFEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno   +3 more
wiley   +1 more source

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