Results 41 to 50 of about 57,488 (215)
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
The role of biodegradable plastics in a sustainable economy: Progress and challenges
Cleaner Engineering and TechnologyThe widespread use of plastics has resulted in significant environmental challenges, including pollution, landfill accumulation, and harm to ecosystems and human health.
Tina Kegl, Yee Van Fan, Lidija Čuček
doaj +1 more source
Сhoice of materials for producing dimensionally stable load-carrying structures
Вестник Самарского университета: Аэрокосмическая техника, технологии и машиностроение, 2018 The article deals with the problems of choosing materials for producing dimensionally stable load-carrying structures of space optical electronic complexes.
V. E. Bitkin +2 more
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Recycled polymer: Green roads for polyester plastics
Green CarbonPlastics are integral to numerous significant social advancements. Nonetheless, their contribution to environmental pollution and climate crises cannot be disregarded, as their negative impact on the environment increases with incremental production ...
Rulin Yang +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
A brief history of the use of plastics
Cambridge Prisms: PlasticsThe appreciation or reception of materials can create a positive or a negative reaction in the user and an individual’s understanding of materials comes from their own experiential knowledge, influence of others, and cultural perception. The condemnation
Louise Dennis
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source