Results 21 to 30 of about 7,704,491 (343)
RAD50 missense variants differentially affect the DNA damage response and mitotic progression
FEBS Letters, EarlyView.RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker +9 more
wiley +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Science SLDM autumn 2009 - Resources [PDF]
, 2009 Collection of resource materials from the autumn 2009 secondary science subject leader development meeting (SLDM) that are designed to provide support and challenge for science departments in the implementation of Assessing Pupils' Progress (APP) and ...
core
Benzobisoxazole cruciforms: a tunable, cross-conjugated platform for the generation of deep blue OLED materials [PDF]
, 2016 Four new cross-conjugated small molecules based on a central benzo[1,2-d:4,5-d′]bisoxazole moiety possessing semi-independently tunable HOMO and LUMO levels were synthesized and the properties of these materials were evaluated experimentally and ...
Cai, Min +9 more
core +1 more source
FEBS Letters, EarlyView.Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia +5 more
wiley +1 more source
Materials Science in Finland [PDF]
Advanced Materials, 2018 This Special Issue is dedicated to current research activities on Materials Science in Finland, providing a collection of outstanding contributions from diverse research groups on the recent progress regarding silicon and silica nanomaterials, DNA nanotechnology, micro/nano‐motors, biomass‐based nanostructures, nanocellulose, 2D layered materials ...
openaire +2 more sources
FEBS Letters, EarlyView.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
Science subject leader development materials: Spring 2010 [PDF]
, 2010 These are the materials from the spring 2010 science subject leader development meetings (SLDM). They provide support and challenge for science departments within the 'Narrowing the Gaps' agenda by focusing on strengthening science learning and teaching.
core
, 2019 Materials science literature contains millions of materials synthesis procedures described in unstructured natural language text. Large-scale analysis of these synthesis procedures would facilitate deeper scientific understanding of materials synthesis ...
Chang, Haw-Shiuan +8 more
core +1 more source
FEBS Letters, EarlyView.Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur +5 more
wiley +1 more source