Results 31 to 40 of about 7,704,491 (343)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

CCT4 promotes tunneling nanotube formation

FEBS Letters, EarlyView.
Tunneling nanotubes (TNTs) are membranous tunnel‐like structures that transport molecules and organelles between cells. They vary in thickness, and thick nanotubes often contain microtubules in addition to actin fibers. We found that cells expressing monomeric CCT4 generate many thick TNTs with tubulin.
Miyu Enomoto, Akiko Asada, Taro Saito, Kanae Ando   +3 more
wiley   +1 more source

How Does Leadership Matter? Developing and Teaching a Definition of Hands-On Science, a Prerequisite for Effective Inquiry Teaching [PDF]

, 2013
This descriptive case study describes leadership skills and planning for setting clear directions by program leaders for a statewide professional development initiative to extend improvement in science teaching and learning.
Sterling, D. R.
core   +1 more source

Materials science and engineering [PDF]

, 1993
During FY-96, work within the Materials Science and Engineering Thrust Area was focused on material modeling. Our motivation for this work is to develop the capability to study the structural response of materials as well as material processing. These capabilities have been applied to a broad range of problems, in support of many programs at Lawrence ...
openaire   +5 more sources

Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes

FEBS Letters, EarlyView.
The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji, Yuko Katayama, Nanase Arata, Mariko Sasaki   +3 more
wiley   +1 more source

Instructional Materials and Implementation of Next Generation Science Standards: Demand, Supply, and Strategic Opportunities [PDF]

, 2017
Next Generation Science Standards (NGSS) are in demand, but the supply of high quality K-12 instructional materials in science is lacking. This disconnect comes at a critical time in the implementation of new science standards, which are now influencing ...
Christine Chopyak, Rodger Bybee
core  

IMP Science Gateway: from the Portal to the Hub of Virtual Experimental Labs in Materials Science

, 2014
"Science gateway" (SG) ideology means a user-friendly intuitive interface between scientists (or scientific communities) and different software components + various distributed computing infrastructures (DCIs) (like grids, clouds, clusters), where ...
Baskova, Olexandra, Bekenev, Lev, Gatsenko, Olexander, Gordienko, Yuri, Stirenko, Sergii, Zasimchuk, Elena   +5 more
core   +1 more source

Mitochondrial fatty acid oxidation is stimulated by red light irradiation

FEBS Letters, EarlyView.
Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera, Camille C. Caldeira da Silva, Maiza Von Dentz, Mauricio S. Baptista, Alicia J. Kowaltowski   +4 more
wiley   +1 more source

Phase-field-crystal models for condensed matter dynamics on atomic length and diffusive time scales: an overview [PDF]

, 2012
Here, we review the basic concepts and applications of the phase-field-crystal (PFC) method, which is one of the latest simulation methodologies in materials science for problems, where atomic- and microscales are tightly coupled. The PFC method operates
Artemev A., Brazowskii S. A., Choudhary M. A., Cross M. C., de Gennes P. G., Dholakia K., Dhont J. K.G., Doi M., Emmerich H., Emmerich H., Evans R., Freund L. B., Frey E., Gray C. G., Groot S. R.d., Gunton J. D., Gyula I. Tóth, György Tegze, Hansen J. P., Hartmut Löwen, Heike Emmerich, Kalikmanov V. I., Kelton K. F., László Gránásy, Pilipenko D., Pismen L. M., Raphael Wittkowski, Reichl L. E., Risken H., Shimoji M., Tegze G., Thomas Gruhn   +31 more
core   +2 more sources

NONLINEARITY IN MATERIALS SCIENCE

International Journal of Modern Physics B, 2001
We discuss the all-important issue of nonlinearity in the physical sciences, with emphasis on its importance in condensed matter physics, where nonlinearity provides a natural mechanism for selective trapping of excitations, such as electrons, at a microscopic scale.
openaire   +3 more sources