Results 111 to 120 of about 1,720,691 (314)

In Situ Synthesis of a Wear Resistant Layer on the Surface of Low Carbon Steel produced by Laser Melt Injection Technology

, 2013
Titanium and his compounds are one of the most frequently used reinforcing particles in iron – ceramic composite materials. These materials will possess special characteristics because they are quenchable, their hardness can be increased by heat ...
Búza, Gábor, Major, Balázs, Mertinger, Valéria   +2 more
core   +1 more source

High-reactivity precursor C2N3H and its photo-induced stepwise growth toward 2D graphitic carbon nitride clusters

iScience
Summary: To investigate the precursors and growth mechanisms of two-dimensional CxNy materials, we performed laser ablation mass spectrometry and spectroscopy on graphitic carbon nitride.
Jiale Li, Yuanhao Liao, Kewei Ding, Kaiwen Liu, Honglin Zeng, Hongguang Xu, Weijun Zheng   +6 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Characterisation of materials for organic photovoltaics

, 2008
Organic solar cells offer the possibility for lightweight, flexible, and inexpensive photovoltaic devices. This thesis studies the physics of a wide range of materials designed for use in organic solar cells.
Thomsen, Elizabeth Alice
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Chiral synthesis on catalysts immobilized in microporous and mesoporous materials

, 2004
This paper reviews the recent progress made in the asymmetric synthesis on chiral catalysts in porous materials and discusses the effects of surface and pores on enantio-selectivity (confinement effect).
Li, C
core   +1 more source

Alkaline earth metal vanadates as sodium-ion battery anodes

Nature Communications, 2017
The development of suitable anode materials is essential to advance sodium-ion battery technologies. Here the authors report that alkaline earth metal vanadates are promising candidates due to the favorable electrochemical properties and interesting ...
Xiaoming Xu, Chaojiang Niu, Manyi Duan, Xuanpeng Wang, Lei Huang, Junhui Wang, Liting Pu, Wenhao Ren, Changwei Shi, Jiasheng Meng, Bo Song, Liqiang Mai   +11 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Material Synthesis

First set of materials synthesized and delivered to partners (15 g)
openaire   +3 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source