Results 121 to 130 of about 1,720,691 (314)

Machine learning-guided synthesis of advanced inorganic materials

, 2020
Synthesis of materials with minimum number of trials is of paramount importance towards the acceleration of advanced materials development. The enormous complexity involved in existing multi-variable synthesis methods leads to high uncertainty, numerous ...
Zhou, Jiadong, Chouhan, Tushar, Golani, Prafful, Xu, Manzhang, Guan, Cuntai, Lu, Yuhao, Tang, Bijun, Xu, Quan, Wang, Han, Liu, Zheng   +9 more
core   +1 more source

Synthesis of functional chalcogenide materials for memory/sensing devices and their integration into artificial sensory systems

International Journal of Extreme Manufacturing
With distinctive phase-change and switching properties, chalcogenide materials have emerged as critical components in various cutting-edge technologies.
Pengfei Liu, Jae Won Heo, Hyeonmin Bong, Jinsik Choe, Huiyoung Lee, Won-Kyu Lee, Myung-Gil Kim, Donghee Son, Joohoon Kang, Taeyong Eom, Sungjin Park, In Soo Kim   +11 more
doaj   +1 more source

Unraveling Mass Transfer and Reaction Processes in CVD-Grown MoS₂ Films: A Multiphysical Field Coupling Study

Applied Sciences
The two-dimensional semiconductor material MoS2, grown via chemical vapor deposition, has shown significant potential to surpass silicon in advanced electronic technologies.
Zhen Yang, Jinwei Lin, Qing Zhang, Yutian Liu, Shujun Han, Yanbin Zhou, Shuo Chen, Shenlong Zhong, Xianli Su, Qingjie Zhang, Xinfeng Tang   +10 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Characterization and fabrication of nanoporous materials by template directed sol-gel methods [PDF]

, 2008
This research project focussed on developing synthetic strategies to fabricate a variety of nanoporous materials ranging the full range of pore sizes from micro to macro using template assisted sol-gel routes.
Hant, Steven Michael
core  

A scalable, chromatography-free synthesis of benzotetramisole

, 2015
The authors thank the Royal Society for a University Research Fellowship (ADS), the EPSRC (EP/J018139/1, DSBD), and GSK (Case award to SRS) for funding. They also thank the European Research Council under the European Union’s Seventh Framework Programme (
Smith, Siobhan Rose, Smith, Andrew David, Shapland, P., Lebl, Tomas, Daniels, David Sydney Bernard   +4 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

NaTiOx‐modified high‐nickel layered oxide cathode for stable sodium‐ion batteries

Carbon Energy
The O3‐type layered cathode with high Ni content has attracted much attention because of its high capacity and simple synthesis process. However, surface side reaction and O3–P3 phase transitions would occur during Na+ insertion/extraction, resulting in ...
Yingcong Liu, Xing Zhou, Dongwei He, Xiaowei Liu, Chao Yang, Dawei Xu, Meilong Wang, Ruitao Sun, Bin Zhang, Jingjing Xie, Jin Han, Wen Chen, Ya You   +12 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source