Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Resorbable Bone-Fixation Materials: Synthesis, Physical-Chemical and Biological Properties. [PDF]
Muzaffarova B, Eranov S, Tillayev S.
europepmc +1 more source
Dataset of solution-based inorganic materials synthesis procedures extracted from the scientific literature. [PDF]
Wang Z +10 more
europepmc +1 more source
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
A Self-Driving Lab for Nano- and Advanced Materials Synthesis. [PDF]
Zaki M, Prinz C, Ruehle B.
europepmc +1 more source
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
Editorial for the Special Issue on Advances in Low-Dimensional Materials: Synthesis, Characterization, and Device Applications. [PDF]
Wu P, Zhang X.
europepmc +1 more source
Magnetic Functional Materials: Synthesis, Characterization and Application: A New Open Special Issue in Materials. [PDF]
Wang H, Wang Y, Yang D.
europepmc +1 more source
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
Zirconium Phosphonate Sorbent Materials-Synthesis, Characterization, and Application for Copper Removal from Acidic Wastewater. [PDF]
Marszałek M +3 more
europepmc +1 more source

