Results 141 to 150 of about 1,720,691 (314)

Autonomous and dynamic precursor selection for solid-state materials synthesis. [PDF]

Nat Commun, 2023
Szymanski NJ, Nevatia P, Bartel CJ, Zeng Y, Ceder G.   +4 more
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Polymer assisted synthesis of functional nano-materials

, 2013
Polymer assisted solution synthesis is a common and versatile strategy for preparation of colloidal inorganic nano-materials with novel morphological and functional properties.
Liang, Yen Nan
core   +1 more source

Unveiling microsecond diffusion bonding phenomena enabled by air plasma spraying zirconia thermal barrier ceramics onto rare earth environmental barrier silicates

Scientific Reports
While global propulsion and energy technology slowly progresses toward cleaner and renewable sources, gas turbine engines are still a workhorse infrastructure in these domains – for which achieving increased operating efficiency and reduced emissions is ...
Edward J. Gildersleeve V, Emine Bakan, Marcin Rasinski, Moritz Kindelmann, Ashok Vayyala, Egbert Wessel, Joachim Mayer, Robert Vaßen   +7 more
doaj   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Perovskite BaTaO₂ N: From Materials Synthesis to Solar Water Splitting. [PDF]

Adv Sci (Weinh), 2023
Hojamberdiev M, Vargas R, Zhang F, Teshima K, Lerch M.   +4 more
europepmc   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Synthesis and Characterization of [1]Benzothieno[3,2-b]benzothiophene-based Porous Organic Polymers for Photocatalysis

reservedDuring the internship at IMDEA Energía, intensive experimental work was carried out focusing on the synthesis, purification, and characterization of COFs (Covalent Organic Frameworks) and CPPs (Conjugated Porous Polymers).
LORENZON, ALESSANDRO
core  

Using Data-Driven Learning to Predict and Control the Outcomes of Inorganic Materials Synthesis. [PDF]

Inorg Chem, 2023
Williamson EM, Brutchey RL.
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source